Results 191 to 200 of about 409,478 (258)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

<i>ABCA4</i>-associated retinopathy complicated by didanosine-associated retinal toxicity. [PDF]

Am J Ophthalmol Case Rep
Nunziata A, Bianco L, Antropoli A, Arrigo A, Bandello F, Mansour AM, Battaglia Parodi M.   +6 more
europepmc   +1 more source

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source

Mechanosensitive dynamics of lysosomes along microtubules regulate leader cell emergence during collective cell migration. [PDF]

Nat Commun
Marwaha R, Manoj D, Rawal S, Khuntia P, Banerjee S, Gupta P, Thurakkal B, Jaiswal M, Das T.   +8 more
europepmc   +1 more source

Beyond the resistive index: value of color-coded duplex sonography parameters in kidney transplantation. [PDF]

Front Nephrol
Konzett K, Neururer S, Tiefenthaler M.
europepmc   +1 more source

Characterization of the Most Resistant and Vulnerable Retinal Ganglion Cell Subtypes in a Chronic Model of Glaucoma in Rat. [PDF]

Invest Ophthalmol Vis Sci
Ruzafa N, Pereiro X, Prieto-López L, Urcola A, Acera A, Vecino E.   +5 more
europepmc   +1 more source

Spatial inequality in school physical education resources in Shaanxi, China (2021-2024): patterns, determinants, and policy implications. [PDF]

Sci Rep
Xu C, Shi B.
europepmc   +1 more source

Dynamic integrin expression, atypical nuclear localization, and spatial distribution during ovarian cancer progression and metastasis. [PDF]

Front Cell Dev Biol
Bano N, Browning JL, Lewis I, Amin M, Zimmerman P, Lee L, Schmelz EM.   +6 more
europepmc   +1 more source

Von Peripherie über Peripherie zum Zentrum

, 2012
openaire   +1 more source