Results 81 to 90 of about 23,652 (216)

Guiding AlphaFold predictions with experimental knowledge to inform dynamics and interactions with VAIRO

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract Structural predictions have reached unprecedented accuracy. They leverage sequence‐specific data to capture all potential interactions a sequence has evolved to fulfill. AlphaFold derives information from three sources: learned parameters capturing intrinsic amino acid secondary structure and environment propensity; models of related proteins ...
Josep Triviño   +14 more
wiley   +1 more source

Characterization and Phylogenetic Analysis of a Novel Uncultivated Magnetotactic Coccus Harbouring Multi‐Chain Magnetosomes

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 1, February 2026.
A novel marine magnetotactic coccus, strain HHB‐1, was isolated from intertidal sediments in Houhai Bay, China. HHB‐1 cells are large coccoid–ovoid bacteria that contain multiple chains of prismatic magnetite magnetosomes and conspicuous Ca/Mg‐rich polyphosphate granules.
Yuzan Che   +6 more
wiley   +1 more source

Ecological, Functional, and Phylogenetic Determinants of Cyanobacterial Biomineralisation

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Cyanobacteria contribute to the global carbon cycle by biomineralising CO2 into solid carbonates. Unlike photosynthesis, biomineralisation is a less‐understood, multifaceted and adaptive metabolic process with significant global impact. It involves cell wall structures, genetic factors, and metabolic pathways that enable mineral formation and help ...
Federica Tiddia   +3 more
wiley   +1 more source

Protein expression and extraction of hard-to-produce proteins in the periplasmic space of Escherichia coli v1 [PDF]

open access: gold, 2020
Cristina Hernández‐Rollán   +4 more
openalex   +1 more source

The Expression of Human Granulocyte Macrophage Colony Stimulating Factor by Heat-Induction in Escherichia coli [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 2004
A self-regulated high-copy number plasmid containing chloramphenicol resistant gene, for the production of recombinant proteins under the regulation of bacteriophage ?pL promoter, was constructed.
doaj  

Activity-Related Conformational Changes in d,d-Carboxypeptidases Revealed by In Vivo Periplasmic Förster Resonance Energy Transfer Assay in Escherichia coli

open access: yesmBio, 2017
One of the mechanisms of β-lactam antibiotic resistance requires the activity of d,d-carboxypeptidases (d,d-CPases) involved in peptidoglycan (PG) synthesis, making them putative targets for new antibiotic development.
Nils Y. Meiresonne   +3 more
doaj   +1 more source

Expression of hepatitis A virus poly(U) polymerase in the periplasmic space of Escherichia coli

open access: yesJournal of General Virology, 1993
A cDNA containing almost all of the hepatitis A virus (HAV) P3 sequences was expressed as a fusion protein with Protein A. A novel poly(U) polymerase activity was detected in the periplasmic space of Escherichia coli cells transformed with this plasmid, and this activity showed many of the expected properties of a picornavirus 3Dpol.
A J, Wolstenholme   +2 more
openaire   +2 more sources

Mutants of Xanthomonas oryzae pv. oryzae Deficient in General Secretory Pathway Are Virulence Deficient and Unable to Secrete Xylanase

open access: yesMolecular Plant-Microbe Interactions, 2000
Xanthomonas oryzae pv. oryzae (Xoo) causes bacterial leaf blight, a serious disease of rice. A virulence- and xylanase-deficient mutant of Xoo was isolated following ethyl methane sulfonate (EMS) mutagenesis.
Suvendra K. Ray   +2 more
doaj   +1 more source

Probiotic‐Based Materials as Living Therapeutics

open access: yesAdvanced Materials, Volume 38, Issue 1, 2 January 2026.
Recent advances in Engineered Living Materials are highlighted, integrating synthetic biology and advanced materials, with a focus on probiotic‐based therapeutics. Probiotic Living Materials hold great potential for biosensing, infection treatment, osteogenesis, wound healing, vaginal and gastrointestinal disorders, and cancer therapy. breakthroughs in
Laura Sabio   +2 more
wiley   +1 more source

Structural Characterization and AI‐Enhanced Modeling of a Broadly Neutralizing Camelid Antibody Against SARS‐CoV‐2 Variants

open access: yesAdvanced Therapeutics, Volume 9, Issue 1, January 2026.
This study characterizes a camelid antibody (B10) with potent neutralizing activity against SARS‐CoV‐2 Wildtype and Omicron variants. Through binding assays, epitope mapping, pseudovirus neutralization, and AI‐driven modeling, the antibody is shown to target conserved RBD regions in a closed Spike conformation.
Katja Hanack   +13 more
wiley   +1 more source

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