Results 21 to 30 of about 42,197 (296)

In vivo performance of antibiotic embedded electrospun PCL membranes for prevention of abdominal adhesions [PDF]

, 2007
The aim of this study was to prepare nonwoven materials from poly(-caprolactone) (PCL) and their antibiotic containing forms by electrospinning, so as to prevent postsurgery induced abdominal adhesions in rats. -Caprolactone was first polymerized by ring-
Bolgen , Nimet, Bölgen , Nimet, Korkusuz, P., Menceloglu, Yusuf Z., Menceloğlu, Yusuf Z., Piskin, Erhan, Pişkin, Erhan, Vargel, İ., Vargel, I.   +8 more
core   +1 more source

A first-in-human, randomized, controlled, subject- and reviewer-blinded multicenter study of Actamax™ Adhesion Barrier [PDF]

, 2016
Purpose: Post-surgical adhesions remain a significant concern following abdominopelvic surgery. This study was to assess safety, manageability and explore preliminary efficacy of applying a degradable hydrogel adhesion barrier to areas of surgical ...
Brucker, Sara Y., Crowe, Alison M., De Wilde, Rudy L., Diamond, Michael P., Estridge, Trudy D., Ford, Ian, Korell, Matthias, Krämer, Bernhard, McConnachie, Alex, Pistofidis, George A., Ritter, Henning, Trew, Geoffrey H., Ziegler, Nicole M.   +12 more
core   +2 more sources

Extracellular Vesicles Derived from Adipose Mesenchymal Stem Cells Promote Peritoneal Healing by Activating MAPK-ERK1/2 and PI3K-Akt to Alleviate Postoperative Abdominal Adhesion

Stem Cells International, 2022
Peritoneal regeneration and repair can alleviate postoperative intraperitoneal adhesions, and mesenchymal stem cells (MSCs) have demonstrated the potential for peritoneal repair and regeneration.
Manyu Shi, Hengchen Liu, Tingting Zhang, Mingzhao Zhang, Xin Tang, Zenan Zhang, Wenjun Lu, Shulong Yang, Zhitao Jiang, Qingbo Cui, Zhaozhu Li   +10 more
doaj   +1 more source

Involvement of the Ubiquitin-Proteasome System in the Formation of Experimental Postsurgical Peritoneal Adhesions

Mediators of Inflammation, 2012
We investigated the Ubiquitin-Proteasome System (UPS), major nonlysosomal intracellular protein degradation system, in the genesis of experimental postsurgical peritoneal adhesions.
Clara Di Filippo, Pasquale Petronella, Fulvio Freda, Marco Scorzelli, Marco Ferretti, Sivestro Canonico, Francesco Rossi, Michele D'Amico   +7 more
doaj   +1 more source

Prevention of post-surgical abdominal adhesions by a novel biodegradable thermosensitive PECE hydrogel.

BMC Biotechnology, 2010
Background Post-operative peritoneal adhesions are common and serious complications for modern medicine. We aim to prevent post-surgical adhesions using biodegradable and thermosensitive poly(ethylene glycol)-poly(ε-caprolactone)-poly(ethylene glycol ...
Yang Bing, Gong ChangYang, Qian ZhiYong, Zhao Xia, Li ZhengYu, Qi XiaoRong, Zhou ShengTao, Zhong Qian, Luo Feng, Wei YuQuan   +9 more
doaj   +1 more source

Release of cholesterol-rich particles from the macrophage plasma membrane during movement of filopodia and lamellipodia. [PDF]

, 2019
Cultured mouse peritoneal macrophages release large numbers of ~30-nm cholesterol-rich particles. Here, we show that those particles represent fragments of the plasma membrane that are pulled away and left behind during the projection and retraction of ...
Fong, Loren G, He, Cuiwen, Heizer, Patrick J, Hu, Xuchen, Jiang, Haibo, Jung, Rachel S, Tontonoz, Peter, Tu, Yiping, Weston, Thomas A, Wohlschlegel, James A, Young, Brian D, Young, Stephen G   +11 more
core   +3 more sources

Mast cells in peritoneal fluid in rats with experimentally induced peritoneal adhesions.

Folia Histochemica et Cytobiologica, 2010
Mast cells (MC) produce, store and release many biologically active substances, especially inflammatory factors, chemotactic substances for neutrophiles, cytokines and prostaglandins.
E Matuszczak, M Oksiuta, W Debek, A Hermanowicz, L Chyczewski, E Dzienis-Koronkiewicz   +5 more
doaj   +1 more source

Rosmarinic acid prevents post-operative abdominal adhesions in a rat model

Scientific Reports, 2022
This study aims to determine the effects of rosmarinic acid which involved the mechanisms to decrease the postoperative peritoneal adhesion formation in rats. Various incisions and removing a 1 × 1 cm piece of peritoneum was used to induce the peritoneal
Ali Kakanezhadi, Mehrdad Rezaei, Abbas Raisi, Omid Dezfoulian, Farshid Davoodi, Hassan Ahmadvand   +5 more
doaj   +1 more source

HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal [PDF]

, 2018
Peritoneal fibrosis is a pathological alteration of the peritoneal membrane occurring in a variety of conditions including peritoneal dialysis (PD), post-surgery adhesions and peritoneal metastases.
Battistelli, Cecilia, Bordoni, Veronica, DE TURRIS, Valeria, Domenici, Alessandro, Mai, Antonello, Manzione, Andrea, Mene', Paolo, Moioli, Alessandra, Noce, Valeria, Palladino, Marco, Rossi, Lucia, Strippoli, Raffaele, Tripodi, Marco, Valente, Sergio, Zwergel, Clemens   +14 more
core   +1 more source

Pharmacological HIF-inhibition attenuates postoperative adhesion formation

Scientific Reports, 2017
Peritoneal adhesions represent a common complication of abdominal surgery, and tissue hypoxia is a main determinant in adhesion formation. Reliable therapeutic options to reduce peritoneal adhesions are scarce.
Moritz J. Strowitzki, Alina S. Ritter, Praveen Radhakrishnan, Jonathan M. Harnoss, Vanessa M. Opitz, Marvin Biller, Julian Wehrmann, Ulrich Keppler, Jana Scheer, Markus Wallwiener, Thomas Schmidt, Alexis Ulrich, Martin Schneider   +12 more
doaj   +1 more source