Results 41 to 50 of about 42,197 (296)

Modified Adenovirus Reduces De Novo Peritoneal Adhesions in Rats and Limits Off-Target Transfection. Role of EZH2 in Adhesion Formation

Journal of Investigative Surgery, 2017
Aim of the study: Adenovector encoding tissue plasminogen activator (tPA) was shown to reduce experimental peritoneal adhesion. We investigated the targeting potential of our modified adenovector, its ability to reduce adhesions and the epigenetic role ...
Hussein M. Atta, Ayman A. Al-Hendy, Salama R. Abdel Raheim, Hend Abdel-Ghany, Khalid A. Nasif, Ahlam M. Abdellah, Nagwa M. Zenhom, Heba S. Kamel   +7 more
doaj   +1 more source

Intestinal Obstruction Secondary to Postoperative Peritoneal Adhesions: the Tolerability of the Conservative Treatment [PDF]

Modern Medicine, 2018
Introduction: The present study aims to determine the mean duration of the conservative management that can be tolerated by the patients with intestinal obstruction secondary to the postoperative peritoneal adhesions, in order to postpone the surgical ...
Simona Bobic, Dragos Davitoiu, Adrian Dorin Bordei, Florian Popa   +3 more
doaj   +1 more source

Targeting the tumor microenvironment in colorectal peritoneal metastases

, 2020
Peritoneal metastasis (PM) occurs in approximately one in four colorectal cancer (CRC) patients. The pathophysiology of colorectal PM remains poorly characterized. Also, the efficacy of current treatment modalities, including surgery and intraperitoneal (
Ceelen, Wim, De Wever, Olivier, Heriot, Alexander G., Narasimhan, Vignesh, Ramsay, Robert G.   +4 more
core   +1 more source

Biologically Targeted Photo‐Crosslinkable Nanopatch to Prevent Postsurgical Peritoneal Adhesion

Advanced Science, 2019
Peritoneal adhesion occurs in a majority of patients following abdominal surgery and can result in significant side effects and complications. Current strategies to minimize adhesions involve the use of nontargeted anatomical barriers that are either ...
Yu Mi, Feifei Yang, Cameron Bloomquist, Youli Xia, Bo Sun, Yanfei Qi, Kyle Wagner, Stephanie A. Montgomery, Tian Zhang, Andrew Z. Wang   +9 more
doaj   +1 more source

Small Bowel Obstruction with a Transition Point in a Patient on Peritoneal Dialysis

Case Reports in Nephrology and Dialysis, 2022
Small bowel obstruction (SBO) is a rare complication of peritoneal dialysis (PD) that is usually seen in patients with encapsulating peritoneal sclerosis.
Babak S. Jazayeri-Moghadass, Ryan Sutherland, Lakir D. Patel, Valeriu Cebotaru   +3 more
doaj   +1 more source

Non-viral Smad7 gene delivery and attenuation of postoperative peritoneal adhesion in an experimental model [PDF]

, 2009
Background: Postoperative intra-abdominal adhesion is associated with high morbidity and mortality. Smad7, a protein that occupies a strategic position in fibrogenesis, inhibits the transforming growth factor (TGF) β/Smad signalling pathway.
Chan, LYY, Cheung, JS, Guo, H, Lai, KN, Leung, JCK, Wu, EX   +5 more
core   +1 more source

Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO) [PDF]

, 2018
Background: Adhesive small bowel obstruction (ASBO) is a common surgical emergency, causing high morbidity and even some mortality. The adhesions causing such bowel obstructions are typically the footprints of previous abdominal surgical procedures.
Abu-Zidan, F.M. (Fikri M.), Ansaloni, L. (Luca), Balogh, Z.J. (Zsolt J.), Bendinelli, C. (Cino), Biffl, W.L. (Walter), Broek, R.P. (R.) ten, Catena, F. (Fausto), Civil, I. (Ian), Coccolini, F. (Federico), Coimbra, R. (Raul), De Moya, M. (Mark), De'Angelis, N. (Nicola), Di Saverio, S. (Salomone), Ferrada, P. (Paula), Fraga, G.P. (Gustavo), Galante, J.M. (Joseph M.), Goor, H. (Harry) van, Inaba, K. (Kenji), Ivatury, R. (Rao), Jeekel, J. (Hans), Kashuk, J.L. (Jeffry L.), Kelly, M.D. (Michael D.), Kirkpatrick, A.W. (Andrew W.), Kluger, Y. (Yoram), Krielen, P. (Pepijn), Latifi, R. (Rifat), Leppaniemi, A. (Ari), Maier, R. (Ron), Moore, E.E. (Ernest), Moore, F.A. (Frederick), Peitzman, A.B. (Andrew), Piscioneri, F. (Frank), Rizoli, S. (Sandro), Sakakushev, B. (Boris), Sartelli, M. (Massimo), Scalea, T. (Thomas), Sugrue, M. (Michael), Søreide, K. (Kjetil), Velmahos, G.C. (George ), Wani, I. (Imtiaz), Weber, D. (Dieter)   +40 more
core   +8 more sources

Gradual Auto-Inoculation as a Factor in the Production of Immunity From the Effects of Septic Infection: [PDF]

, 1893
n/
Binnie, J. F.
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Meloxicam Decreases the Formation of Peritoneal Adhesions in an Experimental Surgical Model in Rats

International Journal of Medical Students, 2017
Background: Inflammatory adhesions result from an inflammatory response of the peritoneum during an intra-abdominal inflammatory process secondary to thermal or mechanical injury, infection, radiation, ischemia, dissection, abrasion or foreign body ...
Luis Alfredo Hernandez Villarroel, Henry Fernandez, Luisa Cesin   +2 more
doaj   +1 more source