Results 101 to 110 of about 408,139 (189)

Semaglutide in type 2 diabetes and chronic kidney disease in Australia: practical clinical considerations from a multidisciplinary panel

Internal Medicine Journal, EarlyView.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) are major causes of morbidity and mortality in people with type 2 diabetes (T2D). Contemporary CKD guidelines increasingly support incorporation of glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) as an additional pillar of cardiorenal therapy alongside renin–angiotensin ...
Eugenia Pedagogos, Roger Chen, Adam Nelson, Sunil Badve, Roy Rasalam, Richard MacIsaac   +5 more
wiley   +1 more source

Encapsulating peritoneal sclerosis in liver transplant

Autopsy and Case Reports, 2021
Encapsulating peritoneal sclerosis occurs due to chronic irritation of the peritoneal surface resulting in inflammation and fibrosis. Encapsulating peritoneal sclerosis usually occurs in patients requiring peritoneal dialysis (PD); however, it may also ...
Gabriel Melki, Abdalla Mohamed, Mina Fransawy Alkomos, Alisa Farokhian, Sohail M. Chaudhry, Varun Patel, Walid J. Baddoura   +6 more
doaj  

A Multidimensional Framework for Interpreting Macrophage Markers in the Era of Cellular Heterogeneity

Immunology, EarlyView.
Macrophage markers should be interpreted as context‐dependent biological readouts rather than deterministic cell identifiers. This Review proposes a multidimensional framework integrating lineage, identity, and functional state across complementary experimental modalities to enable a more accurate interpretation of macrophage heterogeneity.
Alessandro Palma
wiley   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Medicament for preventing peritoneal fibrosis due to long term peritoneal dialysis, comprises MEK 1 or 2 activity modulating agent

, 2008
: NOVELTY - Peritoneal fibrosis is prevented using an agent for modulating MEK 1 and/or MEK 2 activity. USE - For preventing or treating fibrosis of the peritoneal membrane, including peritoneal opacification, tanned peritoneal syndrome, mural ...
M. LOPEZ CABRERA, STRIPPOLI, RAFFAELE, M. A. DEL POZO BARRIUSO   +2 more
core  

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

Reconstruction of deep and perforating corneal defects in dogs—A review (Part II/III): Biomaterials and keratoprosthesis

Veterinary Ophthalmology, Volume 28, Issue 2, Page 532-542, March 2025.
Abstract The surgical reconstruction of severe corneal ulcers is a common and crucial component of the clinical practice of veterinary ophthalmology. Numerous surgical techniques are used in dogs for corneal reconstruction, and these techniques may be categorized by the material used to repair the corneal lesion.
Eric C. Ledbetter, Rick F. Sanchez, Marta Leiva Repiso   +2 more
wiley   +1 more source

Intraoperative cholangiography during open cholecystectomy in 73 dogs with benign gallbladder disease

Veterinary Surgery, EarlyView.
Abstract Objective To evaluate intraoperative cholangiography (IOC) during open cholecystectomy in dogs with benign gallbladder disease, including cases with preoperative common bile duct (CBD) obstruction, and to describe the short‐term outcomes. Study design Retrospective case series. Animals A total of 73 client‐owned dogs.
Ryusei Konno, Yasuyuki Kaneko, Misaki Matsunaga, Tatsuyuki Osuga, Ryota Okadera, Shidow Torisu, Shushi Yamamoto, Kiyokazu Naganobu   +7 more
wiley   +1 more source

Peritoneal MSCs-derived exosomes suppress CCL24 synthesis through miR-320d delivery contributing to the improvement of peritoneal dialysis-associated fibrosis

Scientific Reports
Mesothelial-to-mesenchymal transition (MMT) is a key pathological process driving peritoneal fibrosis in patients undergoing peritoneal dialysis (PD).
Xinhui Zhao, Minhui Xi, Hualin Qi, Jia Xu, Rui Yuan, Danye Shi, Jingyuan Lu   +6 more
doaj   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source