Results 61 to 70 of about 71,423 (312)

Saikosaponin D Inhibits Peritoneal Fibrosis in Rats With Renal Failure by Regulation of TGFβ1/ BMP7 / Gremlin1/ Smad Pathway

Frontiers in Pharmacology, 2021
Peritoneal dialysis (PD) can improve the quality of life of patients with kidney disease and prolong survival. However, peritoneal fibrosis can often occur and lead to PD withdrawal.
Liu Ruiqi, Pei Ming, Su Qihang, Lei Yangyang, Chen Junli, Lin Wei, Gao Chao, Liu Xinyue, Yang Kang, Yang Hongtao   +9 more
doaj   +1 more source

Research advances of endothelial-mesenchymal transition during peritoneal dialysis-related peritoneal fibrosis

Linchuang shenzangbing zazhi, 2021
Peritoneal dialysis is one of renal replacement therapies for patients with end-stage renal disease（ESRD）.Peritoneal dialysis-related peritoneal fibrosis is the most important reason for withdrawing peritoneal dialysis in ESRD patients.Previous studies ...
Liao Meng, Chen Si-jie, Tang Ri-ning, Zhang Xiao-liang   +3 more
doaj  

Experimental systems to study the origin of the myofibroblast in peritoneal fibrosis

Kidney Research and Clinical Practice, 2016
Peritoneal fibrosis is one of the major complications occurring in long-term peritoneal dialysis patients as a result of injury. Peritoneal fibrosis is characterized by submesothelial thickening and fibrosis which is associated with a decline in ...
Manreet Padwal, Peter J. Margetts
doaj   +1 more source

An Unusual Cause of Abdominal Ascites. [PDF]

, 2018
Abdominal ascites is most commonly caused by portal hypertension from liver cirrhosis. When present, portal hypertension is associated with an elevated serum-ascites albumin gradient (SAAG) ≥1.1 g/dL. In contrast, a SAAG < 1.1 g/dL suggests malignancy,
Chak, Eric W, Olson, Kristin A, Wong, Kimberly A   +2 more
core   +2 more sources

Peritoneal fibrosis is mouse strain dependent [PDF]

Nephrology Dialysis Transplantation, 2012
Peritoneal dialysis is a widely used mode of renal replacement therapy in which preservation of the structural and functional integrity of the peritoneal membrane is critical for continued success. Progressive scarring, or fibrosis, in the peritoneal membrane is now well described in peritoneal dialysis patients, but its extent is variable.
Tanya, Bodenham, Nicholas, Topley, Donald, Fraser   +2 more
openaire   +2 more sources

Adipose-derived mesenchymal stem cells attenuate dialysis-induced peritoneal fibrosis by modulating macrophage polarization via interleukin-6

Stem Cell Research & Therapy, 2021
Background Life-long peritoneal dialysis (PD) as a renal replacement therapy is limited by peritoneal fibrosis. Previous studies showed immunomodulatory and antifibrotic effects of adipose-derived mesenchymal stem cells (ADSCs) on peritoneal fibrosis ...
Chih-Yu Yang, Pu-Yuan Chang, Jun-Yi Chen, Bo-Sheng Wu, An-Hang Yang, Oscar Kuang-Sheng Lee   +5 more
doaj   +1 more source

Atrial natriuretic peptide ameliorates peritoneal fibrosis in rat peritonitis model [PDF]

Nephrology Dialysis Transplantation, 2011
Atrial natriuretic peptide (ANP) was recently reported to ameliorate fibrosis in the heart and experimental renal diseases and vascular thickening after balloon injury. Peritoneal fibrosis is an important complication of long-term peritoneal dialysis, and peritonitis is a factor in its onset.
Hiroshi, Kato, Tomohiro, Mizuno, Masashi, Mizuno, Akiho, Sawai, Yasuhiro, Suzuki, Hiroshi, Kinashi, Fumiko, Nagura, Shoichi, Maruyama, Yukihiro, Noda, Kiyofumi, Yamada, Seiichi, Matsuo, Yasuhiko, Ito   +11 more
openaire   +2 more sources

Delayed administration of suramin attenuates peritoneal fibrosis in rats

BMC Nephrology, 2019
Background Peritoneal fibrosis is the most common complication of peritoneal dialysis, but there is currently no effective treatment. We previously reported that suramin pretreatment prevents the development of peritoneal fibrosis in a rat model of ...
Chongxiang Xiong, Na Liu, Xiaofei Shao, Sairah Sharif, Hequn Zou, Shougang Zhuang   +5 more
doaj   +1 more source

p-Cresyl sulfate [PDF]

, 2017
If chronic kidney disease (CKD) is associated with an impairment of kidney function, several uremic solutes are retained. Some of these exert toxic effects, which are called uremic toxins.
Glorieux, Griet, Gryp, Tessa, Vaneechoutte, Mario, Vanholder, Raymond   +3 more
core   +3 more sources

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source