Results 41 to 50 of about 10,452 (228)

T‐cell receptor–like chimeric antigen receptor T cells targeting mesothelin: A first‐in‐human dose‐escalation trial for platinum‐resistant advanced ovarian cancer

open access: yesCancer, Volume 132, Issue 3, 1 February 2026.
Abstract Background Ovarian cancer remains a formidable therapeutic challenge due to late diagnosis, high recurrence rates, and limited treatment options. Mesothelin (MSLN) is highly expressed in ovarian cancer, making it a promising target for immunotherapy.
Yiyang Shan   +7 more
wiley   +1 more source

Sarcomatoid malignant peritoneal mesothelioma: A rare case of sarcomatoid component with monosomy 9 appeared in ascites fluid

open access: yesHuman Pathology: Case Reports, 2019
Sarcomatoid mesothelioma (SM) is the rarest subtype of malignant mesothelioma (MM) with the poorest prognosis. Due to its aggressive nature, early diagnosis and treatment are required for SM, resulting in they significantly improve patient survival ...
Yuri Noda   +3 more
doaj   +1 more source

Pediatric Peritoneal Epithelial Malignant Mesothelioma Case Report

open access: yesCase Reports in Radiology, 2021
We present a 14-year-old boy with peritoneal epithelial malignant mesothelioma (PEMM). While pathology is required to make this diagnosis, radiology plays a crucial role throughout the clinical course of this disease.
Elizabeth Bellew   +5 more
doaj   +1 more source

Metabolic reprogramming of efferocytosis in the tumour microenvironment: From apoptotic‐cell clearance to therapeutic targeting

open access: yesClinical and Translational Medicine, Volume 16, Issue 2, February 2026.
This review systematically deconstructs the pathological efferocytic—metabolic axis in tumours, framing it as a three‐stage, self‐reinforcing cycle: from metabolite‐driven macrophage recruitment, through hijacked surface recognition, to post‐phagocytic metabolic reprogramming that locks in immunosuppression.
Qianlu Yang, Jie Yan, Qianxi Yang
wiley   +1 more source

Recurrent malignant peritoneal mesothelioma treated by a second resection: A case report

open access: yesClinical Case Reports, 2023
Key Clinical Message Malignant peritoneal mesothelioma, a rare and poor prognosis disease, is seldom treated surgically, especially for recurrence. However, early diagnosis and aggressive treatment of primary and recurrent tumors can achieve long‐term ...
Takashi Miyata   +15 more
doaj   +1 more source

Multicystic peritoneal mesothelioma.

open access: yesThe American journal of case reports, 2012
Multicystic peritoneal mesothelioma is a rare disease. It is not certain if it is a benign or a borderline tumor. Although many therapeutic approaches have been used, complete cytoreductive surgery in combination with hyperthermic intraoperative intraperitoneal chemotherapy has gained acceptance.A case of multicystic peritoneal mesothelioma in a 16 ...
Tentes, Antonios-Apostolos   +3 more
openaire   +2 more sources

Tumor‐Associated Macrophages as Therapeutic Targets: Deciphering Interaction Networks and Advancing Clinical Translation

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Tumor‐associated macrophages are the most abundant immune cells in the tumor microenvironment, driving malignant progression and treatment resistance. This review summarizes the protumor mechanisms of TAMs (including phagocytosis modulation, metabolic reprogramming, exosomal communication, and immune interactions), evaluates three major strategies ...
Wurihan Bao   +8 more
wiley   +1 more source

Prolonged response to pemetrexed-based chemotherapy in a patient with peritoneal mesothelioma: a case report and review of the literature

open access: yesPteridines, 2016
Peritoneal mesothelioma is a rare tumor typically presenting with ascites and associated with occupational asbestos exposure with a latency period of 20–40 years.
Študentová Hana   +4 more
doaj   +1 more source

Benign peritoneal cystic mesothelioma mimicking peritoneal tuberculosis

open access: yesClinical Case Reports, 2022
In immunodeficient patients with repetitive peritoneal aggression, cystic mesothelioma should be considered as a differential diagnosis to peritoneal tuberculosis that must be ruled out in endemic countries.
Chayma Soltani   +2 more
doaj   +1 more source

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