Results 81 to 90 of about 17,743 (275)

Immune Modulation in Cancer: The Role of Tumor‐Treating Fields (TTFields)

Current Protocols, Volume 5, Issue 12, December 2025.
Abstract Tumor‐treating fields (TTFields) represent an innovative approach to cancer treatment that leverages low‐intensity (1‐3 V/cm) alternating electric fields operating at intermediate frequencies (100‐300 kHz). These electric fields are specifically designed to disrupt the mitotic process, thereby inhibiting the proliferation of malignant cells ...
Menglan Liu, Maria El Hage, Jihui Zhao, Michael Linnebacher   +3 more
wiley   +1 more source

Malignant peritoneal mesothelioma in a woman with bilateral ovarian serous borderline tumour: Potential interactions between the two diseases

Gynecologic Oncology Reports, 2018
We report a case of a 59-year-old woman with peritoneal malignant mesothelioma and no previous exposure to asbestos with a diagnosis of bilateral ovarian serous borderline tumour with peritoneal implants one year before.
Lorena Losi, Laura Botticelli, Gianluca Taccagni, Ernesto Longinotti, Cesare Lancellotti, Letizia Scurani, Gian Franco Zannoni   +6 more
doaj   +1 more source

A Case of Peritoneal Sarcomatoid Mesothelioma with Absence of Occupationl Exposure to Asbestos [PDF]

Kosin Medical Journal, 2019
Sarcomatoid mesothelioma is not very common, mesothelioma is directly attributable to occupational asbestos exposure, with 90% of cases showing a history of exposure. A 66-year-old male was admitted with an abdominal pain that persisted for 3 weeks.
Seung Hoon Yoo, Hee Man Kim, Jea Kun Park, Mi Sung Kim, Sang Yeop Yi   +4 more
doaj   +1 more source

Value of Ascitic Lipids in the Differentiation between Cirrhotic and Malignant Ascites [PDF]

, 1986
Ascitic fluid concentrations of cholesterol, triglycerides and phospholipids, were compared with ascitic fluid total protein in 40 patients with chronic liver disease, 51patients with various neoplasms and 1 patient with cardiac failure.
Alexander L. Gerbes, Boyer, Dieter Jüngst, Eggstein, Eimermacher, Fiske, Galen, Greene, Gustav Paumgartner, Kirkeby, Nystrom, Paddock, Pare, Polak, Robert Martin, Rovelstad, Röschlau, Sampliner, Schölmerich, Suzuki, Svanberg, Takayama, Tomb   +22 more
core   +1 more source

Immunosenescence: Molecular Mechanisms, Diseases, and Therapeutic Innovations

MedComm, Volume 6, Issue 12, December 2025.
Along with organismal aging or pathogenic processes especially tumor, multiple immune cell types exhibit those well‐established hallmarks of cellular senescent phenotype, mainly characterized by irreversible cell cycle arrest, metabolic disorder, and over production of SASP.
Ninghan Gong, Xiting Pan, Yusi Deng, Jiajia Che, Junhao Bao, Mengqi Wang, Chuan Xu, Xiaowei Liu, Ying Shi   +8 more
wiley   +1 more source

COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSC function [PDF]

, 2010
Background: Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immature cells that accumulates in tumour-bearing hosts. These cells are induced by tumour-derived factors (e.g.
Henk C Hoogsteden, Joachim GJV Aerts, Joost PJJ Hegmans, Joris D Veltman, Margaretha EH Lambers, Menno van Nimwegen, Rudi W Hendriks   +6 more
core   +2 more sources

Mechanical Signaling: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 6, Issue 12, December 2025.
In this review, we summarize cell–ECM interactions and delve into the complex mechanotransduction. We introduce advanced research methods and emerging clinical tools used to study cellular mechanical phenotypes, mechanotransduction, and disease progression. Additionally, we analyze the role of mechanical biomarkers in the development and progression of
Yicen Long, Peng Wang, Jiacheng Lei, Baihai Su, Qiang Wei, Xiaojing Liu   +5 more
wiley   +1 more source

Content validity and ePRO usability of the BPI-sf and “worst pain” item with pleural and peritoneal mesothelioma

Journal of Patient-Reported Outcomes, 2018
Background The Brief Pain Inventory-short form (BPI-sf) is widely used in self-reported pain assessment, incorporates pain numeric rating scales (NRS) and is commonly utilized in electronic format in clinical trials, however, there is no published ...
Heather L. Gelhorn, Sonya Eremenco, Anne M. Skalicky, Zaneta Balantac, Tricia Cimms, Katarina Halling, Chris Sexton   +6 more
doaj   +1 more source

Intraperitoneal chemotherapy for peritoneal metastases : an expert opinion

, 2020
Introduction: The rationale for intraperitoneal (IP) drug delivery for patients with peritoneal metastases (PM) is based on the pharmacokinetic advantage resulting from the peritoneal-plasma barrier, and on the potential to adequately treat small, poorly
Braet, Helena, Ceelen, Wim, Remaut, Katrien, Van Ramshorst, Gabrielle, Willaert, Wouter   +4 more
core   +1 more source

Current and prospective pharmacotherapies for the treatment of pleural mesothelioma [PDF]

, 2017
Introduction: Mesothelioma is a rare asbestos-linked cancer with an expected incidence peak between 2015–2030. Therapies remain ineffective, thus developing and testing novel treatments is important for both oncologists and researchers. Areas covered:
Aoe K, Della Pepa C, Doyle C, Dudek AZ, Flores RM, Fujimoto N, Garland LL, Ismail-Khan R, Janne PA, Kalra N, Kurai J, Leigh RA, Neumann V, Pache JC, Papa S, Papaspyros S, Porpodis K, Ramalingam SS, Sterman DH, Suzuki Y, Zarogoulidis P   +20 more
core   +2 more sources