Results 111 to 120 of about 591,059 (370)

Perioperative Factors Affecting Successful On-table Tracheal Extubation after Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Retrospective Study

open access: yesJournal of Onco-Anaesthesiology and Perioperative Medicine
Background and Aims: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) is an advanced, complex and curative surgical procedure in primary and secondary peritoneal cancers.
Suparna Mitra Barman   +5 more
doaj   +1 more source

PBLD Orchestrates the STING‐Mediated Antiviral Immune Response and Autoimmune Diseases

open access: yesAdvanced Science, EarlyView.
During viral infection, PBLD expression is downregulated, thereby subverting host antiviral defenses and promoting viral replication. This study identifies PBLD as a positive regulator of STING‐induced type I interferon activation and delineated the molecular network underlying PBLD‐mediated antiviral immunity and autoimmune pathogenesis, highlighting ...
Peili Hou   +17 more
wiley   +1 more source

Metastatic Diffuse Intrinsic Pontine Glioma to the Peritoneal Cavity Via Ventriculoperitoneal Shunt: Case Report and Literature Review

open access: yesJournal of Neurological Surgery Reports, 2015
Extraneural metastatic disease resulting from a primary central nervous system neoplasm is a rare clinical finding in the pediatric population. We report a case of peritoneal glioblastoma carcinomatosis following placement of a ventriculoperitoneal shunt
Ramon Francisco Barajas Jr.   +8 more
doaj   +1 more source

Treatment options for PNET liver metastases. a systematic review [PDF]

open access: yes, 2018
Pancreatic neuroendocrine tumors (PNETs) are rare pancreatic neoplasms. About 40-80% of patients with PNET are metastatic at presentation, usually involving the liver (40-93%). Liver metastasis represents the most significant prognostic factor.
Aurello, Paolo   +8 more
core   +1 more source

En bloc resection of extra-peritoneal soft tissue neoplasms incorporating a type III internal hemipelvectomy: a novel approach

open access: yesWorld Journal of Surgical Oncology, 2012
BackgroundA type III hemipelvectomy has been utilized for the resection of tumors arising from the superior or inferior pubic rami.MethodsIn eight patients, we incorporated a type III internal hemipelvectomy to achieve an en bloc R0 resection for tumors ...
S. Reddy, N. Bloom
semanticscholar   +1 more source

Stromal Cell‐Mast Cell Communication Orchestrates Anti‐Viral Immunity in the Meninges

open access: yesAdvanced Science, EarlyView.
This study delineates the spatial distribution and postnatal maturation of meningeal mast cells and uncovers their essential role in antiviral immunity. Using genetic models, mast cells are shown to promote CD8⁺ T cell infiltration and viral clearance via IL‐33 receptor signaling and synergistic activation by IL‐33 and ATP from infected stromal cells ...
Qingqing Li   +7 more
wiley   +1 more source

Delayed phlegmon with gallstone fragments masquerading as soft tissue sarcoma. [PDF]

open access: yes, 2016
Complications from lost gallstones after cholecystectomy are rare but varied from simple perihepatic abscess to empyema and expectoration of gallstones.
Bateni, Cyrus P   +3 more
core   +1 more source

From Sample to Mixed Reality: A Translational 3D MALDI Imaging Platform for Advanced 3D Spatial Omics Analysis of 3D Cell Culture Disease Models

open access: yesAdvanced Science, EarlyView.
A comprehensive technology platform enables high‐fidelity, volumetric MALDI imaging of 3D cell cultures by integrating custom embedding molds, a semi‐automated computational framework for 3D reconstruction, voxel‐instead of pixel‐based biomarker discovery, and immersive mixed reality data exploration.
Stefania Alexandra Iakab   +16 more
wiley   +1 more source

TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis [PDF]

open access: yes, 2015
Truncating mutations in the tumor suppressor gene adenomatous polyposis coli (APC) are the initiating step in the vast majority of sporadic colorectal cancers, and they underlie familial adenomatous polyposis (FAP) syndromes.
Creytens, David   +8 more
core   +3 more sources

NIR Ratiometric Fluorescent Antibody‐Drug Conjugate for Metastatic Ovarian Cancer Theranostics and Treatment Response Monitoring

open access: yesAdvanced Science, EarlyView.
In vivo optical imaging enhances antibody‐drug conjugate (ADC) optimization by enabling real‐time monitoring of stimulus‐responsive drug behavior. We report n501‐CYMMAF, a ratiometric theranostic with strong target affinity and low‐dose efficacy for ovarian metastasis.
Cheng Li   +8 more
wiley   +1 more source

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