Results 211 to 220 of about 61,454 (363)

Rodent monocyte‐derived macrophages do not express CD163: Comparative analysis using macrophages from living boreoeutherians

Developmental Dynamics, EarlyView.
Abstract Background CD163 is a scavenger receptor predominantly expressed on the surfaces of macrophages in various mammalian species and is a marker of anti‐inflammatory (M2‐like) macrophages. High density of CD163‐positive tumor‐associated macrophages (TAMs) is associated with worse prognosis in various patient tumors.
Yoichi Saito, Yukio Fujiwara, Yasuka L. Yamaguchi, Satomi S. Tanaka, Kyoko Miura, Yoshiyuki Hizukuri, Kyoko Yamashiro, Yasuhiro Hayashi, Yuta Nakashima, Yoshihiro Komohara   +9 more
wiley   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Immunomodulatory Nanozymes Eradicate Intracellular Infections and Rescue Immunoparalysis for Treating Multidrug‐Resistant Bacterial Sepsis

Exploration, EarlyView.
Immunomodulatory nanozymes enable in situ macrophages engineering and orchestrate systemic innate‐adaptive immune response to eradicate intracellular bacteria and rescue immunoparalysis for treating multidrug‐resistant bacterial sepsis. ABSTRACT Sepsis and their sequelae are the leading causes of death in intensive care units, with limited therapeutic ...
Xuancheng Du, Zhenzhen Dong, Yan Yan, Yuan Gong, Meili Yuan, Chengtai Ma, Lingqi Xu, Yuanyuan Qu, Minhan Qu, Peng Pan, Weifeng Li, Wenyan Hao, Yingyi Yang, Xiangdong Liu, Mingwen Zhao, Zhenjiang Bai, Jiang Huai Wang, Jian Wang, Yong‐Qiang Li, Huiting Zhou   +19 more
wiley   +1 more source

Molecular Characterization of Peritoneal Involvement in Primary Colon and Ovary Neoplasm: The Possible Clinical Meaning of the P2X7 Receptor-Inflammasome Complex

, 2021
Anna Solini, Luigi Cobuccio, Chiara Rossi, Federico Parolini, Edoardo Biancalana, Stefania Cosio, Massimo Chiarugi, Angiolo Gadducci   +7 more
openalex   +1 more source

Isolation and Extraction of Gentian Polysaccharide and Its Protective Effect on Chemical Liver Injury

Food Safety and Health, EarlyView.
The water‐soluble polysaccharide GSBP‐N‐a‐1 with an average molecular weight of 3.82 kDa was successfully isolated and purified from Gentiana scabra. It was confirmed that the crude polysaccharides of Gentiana scabra could inhibit oxidative stress and inflammatory response by activating the Nrf2‐HO‐1 pathway, and significantly alleviate the chemical ...
Tianjiao Fu, Yan Dong, Guangxin Yuan
wiley   +1 more source

Systemic chemotherapy in patients with unresectable pseudomyxoma peritonei from low-grade appendiceal mucinous neoplasms: a case series. [PDF]

J Gastrointest Oncol
Vierra M, Morgan RB, Ostowari A, Turaga KK, Shergill A, Eng OS.   +5 more
europepmc   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

The Many Faces of the Angry Peritoneum. [PDF]

Diagnostics (Basel)
Ambrosetti MC, Bariani M, Zamboni GA, Valletta R, Bonatti M.   +4 more
europepmc   +1 more source

Occurrence of bladder metastasis 10 years after surgical removal of a primary gastric cancer: a case report and review of the literature [PDF]

, 2019
András, Csilla, Csiki, Emese, Csiki, Zoltán, Enyedi, Attila, Flaskó, Tibor, Garami, Zoltán, Horváth, Zsolt, Pósán, János, Tanyi, Miklós, Tóth, László   +9 more
core   +1 more source

Correction to: Surveillance of Low-Grade Appendiceal Mucinous Neoplasms With Peritoneal Metastases After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: Are 5 Years Enough? A Multisite Experience [PDF]

, 2019
Daniel Solomon, Eliahu Y. Bekhor, Natasha Leigh, Yash Maniar, Linsay Totin, Margaret Hofstedt, Samantha N. Aycart, Jacquelyn Carr, Samuel Ballentine, Deepa Magge, Benjamin J. Golas, Reetesh K. Pai, Alexandros D. Polydorides, David L. Bartlett, Daniel M. Labow, Haroon A. Choudry, Umut Sarpel   +16 more
openalex   +1 more source