Results 181 to 190 of about 180,692 (332)

THE PERITONEUM AS RELATED TO PERITONITIS

, 1928
Vernon C. David, Joseph L. Spaizks
openalex   +2 more sources

Reactive Cysteines in Proteins are the Dominant Reductants for Platinum(IV) Prodrug Activation in Live Cells

Angewandte Chemie, EarlyView.
Pt‐Luc was developed as a pioneering bioluminescent reporter for real‐time monitoring of Pt(IV) reduction in live cells. Using this advanced reporter, we identified that reactive cysteines in proteins, rather than those in small molecules, predominantly mediate the reduction of Pt(IV) prodrugs.
Shu Chen, Wang Peng, Houzong Yao, Zhiqin Deng, Zhao Yue, Gongyuan Liu, Jiaqian Xu, Naixin Lin, Weikang Xu, Jianbo Yue, Guangyu Zhu   +10 more
wiley   +2 more sources

Abnormal DNA Methylation Profile Suggests the Extension of the Clinical Spectrum of the SETD2‐Related Disorders to a Syndromic Multiple Tumor Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT SETD2 has an essential role in epigenetic regulation. SETD2 pathogenic variants cause neurodevelopmental disorders (SETD2‐NDDs) that most commonly include various degrees of intellectual disability and behavioral disorders, macrocephaly, brain malformations, and generalized overgrowth.
Marie Lucain, Antonio Vitobello, Bekim Sadikovic, Juliette Albuisson, Léa Gaudillat, Martin Chevarin, Julien Maraval, Christel Thauvin‐Robinet, Jennifer Kerkhof, Christophe Philippe, Sophie Nambot, Laurence Faivre   +11 more
wiley   +1 more source

Molecular Profiling and Tumor Microenvironment in Sinonasal Mucosal Melanoma as Biomarkers for Enhanced Prognostic Stratification

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Sinonasal mucosal melanoma (SNMM) is a rare and aggressive melanoma subtype with a notably poor prognosis. Despite molecular characterization advances, SNMM remains clinically challenging, highlighting the need for detailed molecular profiling.
Manuel Molina‐Garcia, Maria Jesus Rojas‐Lechuga, Cristobal Langdon, Judit Mateu, Jaume Bague, Teresa Torres, Vinicius G. de Souza, Manuel Bernal‐Sprekelsen, Isam Alobid, Rui Milton Patricio da Silva‐Júnior, Susana Puig   +10 more
wiley   +1 more source

TWO CASES OF TUBERCULOUS INFECTION OF THE PERITONEUM [PDF]

, 1909
W. H. ALLPORT
openalex   +1 more source

Animal models of cisplatin‐induced neuropathic pain

Animal Models and Experimental Medicine, EarlyView.
This article illustrates the modeling process of a cisplatin‐induced neuropathic pain model in rats or mice. Multiple modeling tests are required for rats or mice before, during, and after modeling. The appropriate injection method, dose, and modeling method are selected, and multiple assays are chosen for evaluation and comparison.
Ningxin Li, Mingzhu Li, Shengbo Jin, Jun Yu, Hongzhe Wei, Wenping Wang, Siyao Ma, Yuxin Jiang, Qian Liu, Huini Yao   +9 more
wiley   +1 more source

The peritoneum: healing, immunity, and diseases

Journal of Pathology, 2017
A. Capobianco, Lucia Cottone, A. Monno, A. Manfredi, P. Rovere-Querini   +4 more
semanticscholar   +1 more source

Application of humanized mice in the safety experiments of antibody drugs

Animal Models and Experimental Medicine, EarlyView.
The graphical abstract of this review highlights the critical role of humanized mice in the safety evaluation of antibody drugs. First, the inherent immunogenicity of antibody drugs can lead to the production of antidrug antibodies and hypersensitivity reactions on repeated administration.
Zhimin Sun, Mengyun Gu, Zixuan Yang, Lei Shi, Liyuan Zhao, Minhui Zheng, Yan Wang, Wei Zhang, Kexin Han, Naping Tang   +9 more
wiley   +1 more source

PRIMARY CLOSURE OF PERITONEUM IN ACUTE APPENDICITIS WITH PERFORATION

, 1939
Richard J. Warren
openalex   +2 more sources

TUBERCULOSIS OF THE PERITONEUM. [PDF]

, 1902
Alexander Morison
openalex   +1 more source