Results 41 to 50 of about 211,167 (338)

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail   +3 more
wiley   +1 more source

Repeated streptococcal peritoneal dialysis-related peritonitis following stomatitis and gingival bleeding: a case report

open access: yesRenal Replacement Therapy, 2022
Background Identification of the pathogenesis of peritoneal dialysis (PD)-related peritonitis is important. However, identification of endogenous peritonitis, especially hematogenous infection, is difficult, and there are few reports of endogenous ...
Kento Fukumitsu   +7 more
doaj   +1 more source

Requirement of endogenous tumor necrosis factor/cachectin for recovery from experimental peritonitis [PDF]

open access: yes, 1990
By intrasplenic immunization we raised a rat mAb (mAb V1q; IgG2a, kappa) with a potent neutralizing activity against natural mouse TNF (1 microgram/ml mAb V1q/100 U/ml TNF). mAb V1q was used to study the role of endogenous TNF in experimental peritonitis
Echtenacher, B.   +3 more
core  

Stretchable, Multiplexed, and Bimodal Sensing Electronic Armor for Colonoscopic Continuum Robot Enhanced by Triboelectric Artificial Synapse

open access: yesAdvanced Materials, EarlyView.
Colonoscopic continuum robots lack sensing, endangering intestinal tissue. An ideal sensing array is hard to integrate. This work introduces a 3D crosslinked stretchable E‐armor with full‐coverage and multiplexing. It has bimodal sensing, forms a triboelectric synapse, uses CNN‐LSTM, and has a hydrogel and innovative triboelectric materials.
Yuyang Sun   +8 more
wiley   +1 more source

Educating end-stage renal disease patients on dialysis modality selection: a clinical advice from the European Renal Best Practice (ERBP) advisory board [PDF]

open access: yes, 2010
status ...
Bammens, Bert   +7 more
core   +2 more sources

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

open access: yesAdvanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao   +14 more
wiley   +1 more source

Meconium peritonitis resulting from different etiologies in siblings: a case report

open access: yesBMC Pediatrics, 2020
Background Meconium peritonitis is defined as aseptic chemical inflammation caused by intrauterine bowel perforation. The underlying causes of bowel perforation include intestinal atresia, midgut volvulus, intussusception, congenital bands, and meconium ...
Kyung Hee Park   +5 more
doaj   +1 more source

TLR4 and NLRP3 Caspase 1- IL-1β- Axis are not Involved in Colon Ascendens Stent Peritonitis (Casp)-Associated Heart Disease [PDF]

open access: yes, 2018
Hemodynamic collapse and myocardial dysfunction are among the major causes ofdeath in severe sepsis. The purpose of this study was to assess the role played by TLR4and by the NLRP3 inflammasome in the cardiac dysfunction that occurs after ...
Branda, Hugo Justino   +10 more
core   +2 more sources

MCT1‐mediated Lactate Shuttle to Mitochondria Governs Macrophage Polarization and Modulates Glucose Homeostasis by Affecting β Cells

open access: yesAdvanced Science, EarlyView.
This study demonstrates that the transport of lactate to the mitochondria is of critical importance in determining the functions of macrophages by altering mitochondrial respiration. In macrophages, this lactate transport mechanism regulates glucose homeostasis by influencing the functions of insulin‐secreting cells in the pancreatic islets.
Lingling Chen   +9 more
wiley   +1 more source

Peritoneal Effluent Cell-Free DNA Sequencing in Peritoneal Dialysis Patients With and Without PeritonitisPlain Language Summary

open access: yesKidney Medicine, 2022
Rationale & Objective: Conventional culture can be insensitive for the detection of rare infections and for the detection of common infections in the setting of recent antibiotic usage.
Philip Burnham   +18 more
doaj  

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