Results 51 to 60 of about 226,929 (358)

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

Vasoconsrictive and vasodilatative imbalance at experimental fecal peritonitis

open access: yesJournal of Education, Health and Sport, 2019
Peritonitis problem today one of the most urgent issues in the field of clinical pathological physiology and abdominal surgery. According to various data, mortality in peritonitis is 18.3 - 62.8%.
I. V. Savytskyi   +6 more
doaj   +3 more sources

Amino acid changes in the spike protein of feline coronavirus correlate with systemic spread of virus from the intestine and not with feline infectious peritonitis [PDF]

open access: yes, 2014
Recent evidence suggests that a mutation in the spike protein gene of feline coronavirus (FCoV), which results in an amino acid change from methionine to leucine at position 1058, may be associated with feline infectious peritonitis (FIP).
Day, Michael J   +6 more
core   +5 more sources

Utilizing Proteolytic‐Resistant Nano‐Short Peptide Based on Naphthyl Tail‐Anchored to Combat Bacterial Infections

open access: yesAdvanced Science, EarlyView.
Antimicrobial peptides (AMPs) show potential as alternatives to antibiotics for bacterial infections; however, their susceptibility to proteases limits wider application. In this study, N4 nanofibers are constructed by integrating anti‐enzymolysis motif into the self‐assembly system triggered by naphthyl‐anchored.
Xi Yan   +6 more
wiley   +1 more source

Peritonitis index caused by abdominal combat trauma

open access: yesУкраїнський журнал військової медицини
Objective: to create a scale for assessing the peritonitis in combat abdominal trauma to determine surgical tactics Materials and methods. An analysis of surgical care and treatment of 227 wounded who received combat abdominal trauma in the ...
I. V. Sobko   +3 more
doaj   +1 more source

Identification of a Pair of Linear or Cyclic Naturally Inspired Bifunctional Lipopeptide Antibiotics That Overcome Antimicrobial Resistance

open access: yesAdvanced Science, EarlyView.
The underexplored bacterial genus Aquimarina harbors a large biosynthetic potential for discovering new antibiotics. Here, the authors identify a pair of linear or cyclic bifunctional cationic lipopeptide antibiotics, aquicidine L and C4, inspired by the aquicidine gene cluster from Aquimarina.
Lei Li, Yiwen Zhou, Yuzhu Wu
wiley   +1 more source

Laeverin is Cell‐Surface Target for Liquid‐Phase Metastasizing Cancer Cells

open access: yesAdvanced Science, EarlyView.
This study revealed that epithelial cancer cells in the floating phase induce the expression of laeverin (LVRN) that is a trophoblast‐specific and cell‐surface immunoregulatory factor and showed that anti‐LVRN ADC is a promising agent that can attack cancer cells in the metastatic liquid phase and block further distant metastasis.
Haruki Kasama   +17 more
wiley   +1 more source

Repeat peritonitis in peritoneal dialysis : A cohort study

open access: yesBulletin de la Dialyse à Domicile
Introduction: The understanding of the pathophysiological mechanisms of repeat peritonitis, defined as the occurrence of peritonitis more than 4 weeks after the end of appropriate antibiotic treatment for a previous episode involving the same germ ...
Nabil Hmaidouch   +4 more
doaj   +1 more source

Endoscopic Submucosal Dissection Versus Laparoscopic and Endoscopic Cooperative Surgery for Superficial Duodenal Epithelial Tumors: A Multicenter Retrospective Study

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aims This study aimed to compare the clinicopathological features and short‐term outcomes of endoscopic submucosal dissection (ESD) and laparoscopic and endoscopic cooperative surgery (LECS) for superficial duodenal epithelial tumors (SDETs) and investigate the risk factors for severe adverse events (AEs).
Takuo Takehana   +20 more
wiley   +1 more source

Incidence and outcome of encapsulating peritoneal sclerosis [PDF]

open access: yes, 2016
Background: Studies report variation in the incidence and outcomes of encapsulating peritoneal sclerosis (EPS). This study reports the incidence and outcome of EPS cases in a national cohort of peritoneal dialysis (PD) patients.
Mactier, Robert A.   +2 more
core   +2 more sources

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