Results 151 to 160 of about 43,516 (333)

MRI Diffusion Tensor Image Analysis Along the Perivascular Space: Effects of Mean Tract Orientation Divergence

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background The diffusion tensor image analysis along the perivascular space (DTI‐ALPS) index is an established term, and ongoing research aims to explore underlying mechanisms. Hypothesis DTI‐ALPS measures are influenced by subject‐specific orientational differences of the projection and association fibers. Study Type Prospective.
Dávid Bognár, Gergely Orsi, Csirmaz Benedek, Szilvia A. Nagy, Gergely Darnai, Barnabás Dudás, Ákos Arató, Norbert Kovács, József Janszky, Gábor Perlaki   +9 more
wiley   +1 more source

Long coronavirus disease-related persistent poor sleep quality and progression of enlarged perivascular spaces. A longitudinal study [PDF]

, 2022
Óscar H. Del Brutto, Robertino M. Mera, Aldo F. Costa, Denisse A. Rumbea, Bettsy Y. Recalde, Pablo R. Castillo   +5 more
openalex   +1 more source

Co‐ and Multi‐Pathologies in Parkinson's Disease: An International Parkinson and Movement Disorder Society Scientific Issues Committee Review

Movement Disorders, EarlyView.
Abstract Parkinson's disease (PD) has been historically defined as a disease of striatal dopamine deficiency secondary to degeneration of dopaminergic neurons in the substantia nigra pars compacta, related to the presence of Lewy bodies and Lewy neurites.
Michele Matarazzo, Per Borghammer, Inas Elsayed, Jennifer G. Goldman, Yue Huang, Katja Lohmann, Per Svenningsson, Lorraine V. Kalia, Daniela Berg, Jeffrey H. Kordower, the MDS Scientific Issues Committee   +10 more
wiley   +1 more source

Aggravation of Enlarged Perivascular Spaces in the Centrum Semiovale of Patients with Aneurysmal Subarachnoid Hemorrhage

, 2021
Jina Kim, Bio Joo, Jin Woo Kim, Mina Park, Sung Jun Ahn, Sang Kyu Park, Sang Hyun Suh   +6 more
openalex   +2 more sources

A Phase 1 Study of Convection‐Enhanced Delivery of Intraputaminal AAV2‐GDNF in Advanced Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is a progressive neurodegenerative disorder. Neurotrophic therapeutic approaches have been limited in part by incomplete delivery to the putamen. We developed image‐guided convection‐enhanced delivery with real‐time monitoring to improve intraputaminal distribution of neurotrophic gene therapy. Objectives To
John D. Heiss, Debra J. Ehrlich, Codrin Lungu, Joseph Y. Choi, Gretchen Scott, Irene Dustin, Dima A. Hammoud, Peter Herscovitch, Russell R. Lonser, Kareem A. Zaghloul, Krystof Bankiewicz   +10 more
wiley   +1 more source

Larger perivascular space volume fraction is associated with worse post-stroke sensorimotor outcomes: An ENIGMA analysis [PDF]

Stuti Chakraborty, Jeiran Choupan, Octavio Marin‐Pardo, Mahir H. Khan, Giuseppe Barisano, Bethany P. Tavenner, Miranda R. Donnelly, Aisha Abdullah, Justin W. Andrushko, Nerisa Banaj, Michael R. Borich, Lara A. Boyd, Cathrin M. Buetefisch, Adriana Bastos Conforto, Steven C. Cramer, Martin Domín, Adrienne N. Dula, Jennifer K. Ferris, Brenton Hordacre, Steven A. Kautz, Neda Jahanshad, Martín Lotze, Kyle Nishimura, Fabrizio Piras, Kate Revill, Nicolas Schweighofer, Surjo R. Soekadar, Shraddha Srivastava, Sophia I. Thomopoulos, Daniela Vecchio, Lars T. Westlye, Carolee J. Winstein, George F. Wittenberg, Kristin A. Wong, Paul M. Thompson, Sook‐Lei Liew   +35 more
openalex   +1 more source

MRI-visible perivascular spaces are associated with cerebrospinal fluid biomarkers in Parkinson’s disease

, 2020
Yi Fang, Luyan Gu, Jun Tian, Shaobing Dai, Ying Chen, Ran Zheng, Xiaoli Si, Chongyao Jin, Zhe Song, Yaping Yan, Xinzhen Yin, Jiali Pu, Baorong Zhang   +12 more
openalex   +2 more sources

Brain Clearance of Contrast Agent in Intravenous DCE‐MRI Is Measurable and Cannot Be Explained by Clearance Across the BBB Alone

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To determine the feasibility of measuring brain clearance of gadolinium contrast agent using standard intravenous DCE‐MRI acquisitions and evaluate the contribution of blood–brain barrier (BBB) and non‐BBB clearance routes. Methods Uptake and extended Tofts models were fit to DCE‐MRI data from people with Parkinson's disease, post ...
Martin Kozár, Ioana‐Emilia Mosneag, Sarah Al‐Bachari, Igor Chernyavsky, Geoff J. M. Parker, Hervé Boutin, Laura M. Parkes, Ingo Schiessl, Ben R. Dickie   +8 more
wiley   +1 more source

The glymphatic system: A new insight into the understanding of neurological diseases

Brain-X
The glymphatic system (GS) is a newly discovered transport system in the central nervous system (CNS) that plays a crucial role in maintaining homeostasis by facilitating the clearance of metabolic waste and fluid transport. This groundbreaking discovery
Junbo Liao, Zhihan An, Quan Cheng, Yaxue Liu, Yibing Chen, Zhangjie Su, Ahsan Muhammad Usman, Zhi Tang, Gelei Xiao   +8 more
doaj   +1 more source

Mesenchymal stem cells injected into carotid artery to target focal brain injury home to perivascular space

, 2020
A Andrzejewska, Sylwia Dabrowska, Błażej Nowak, Piotr Walczak, Barbara Łukomska, Mirosław Janowski   +5 more
openalex   +1 more source