Correlation between visual function, neurodevelopmental outcome, and magnetic resonance imaging findings in infants with periventricular leucomalacia [PDF]
Archives of Disease in Childhood: Fetal and Neonatal Edition, 2000 Aim-To evaluate the correlation between visual function and neurodevelopmental outcome in children with periventricular leucomalacia at 1 and 3 years.
Eugenio Mercuri, Andrea Guzzetta
exaly +3 more sources
Motor pathway injury in patients with periventricular leucomalacia and spastic diplegia [PDF]
Brain, 2011 Periventricular leucomalacia has long been investigated as a leading cause of motor and cognitive dysfunction in patients with spastic diplegic cerebral palsy. However, patients with periventricular leucomalacia on conventional magnetic resonance imaging do not always have motor dysfunction and preterm children without neurological abnormalities may ...
Jong Doo, Lee +11 more
openaire +5 more sources
Motor Pathway Injury with Periventricular Leukomalacia and Spastic Diplegia
Pediatric Neurology Briefs, 2011 The relationship between motor pathway injury and motor impairment was investigated by voxelwise correlation analysis in 43 patients (median age 12 years) with periventricular leucomalacia and spastic diplegia at Yonsei University College of Medicine ...
J Gordon Millichap
doaj +2 more sources
Optic disc morphology may reveal timing of insult in children with periventricular leucomalacia and/or periventricular haemorrhage. [PDF]
Br J Ophthalmol, 2003 To evaluate the relation between optic disc morphology and timing of periventricular white matter damage, defined as either periventricular leucomalacia (PVL) or periventricular haemorrhage (PVH), as estimated by neuroradiology.35 children with periventricular white matter damage who had had neuroradiology performed and ocular fundus photographs taken ...
Jacobson L +4 more
europepmc +4 more sources
Ultrasound diagnosis and neurodevelopmental outcome of localised and extensive cystic periventricular leucomalacia. [PDF]
Arch Dis Child Fetal Neonatal Ed, 2001 AIMS To compare the ultrasound (US) evolution and neurodevelopmental outcome of infants with localised (grade II) and extensive (grade III) cystic periventricular leucomalacia (c-PVL). METHODS Over a nine year period, c-PVL was diagnosed in 96/3451 (
Pierrat V +5 more
europepmc +4 more sources
Periventricular leucomalacia and intraventricular haemorrhage in the preterm neonate. [PDF]
Arch Dis Child, 1986 Two hundred very low birthweight infants were prospectively scanned to ascertain the incidence of periventricular leucomalacia (PVL) and haemorrhage. Before collection of data, clear definitions of ultrasound abnormalities believed to represent PVL and intraventricular haemorrhage were described.
Trounce JQ, Rutter N, Levene MI.
europepmc +4 more sources
Plasma hypoxanthine: a marker for hypoxic-ischaemic induced periventricular leucomalacia? [PDF]
Arch Dis Child, 1992 Cerebral ischaemia of the immature brain may result in cavitating periventricular leucomalacia (PVL), an important association of cerebral palsy. Hypoxanthine measured by high performance liquid chromatography was used as a marker of peripartum hypoxia and ischaemia in 116 infants at risk of PVL. PVL was detected by ultrasound.
Russell GA, Jeffers G, Cooke RW.
europepmc +4 more sources
Pediatric Radiology, 2006 Magnetization transfer imaging assesses the myelination status of the brain.To study the progress of myelination in children with periventricular leucomalacia (PVL) by measuring the magnetization transfer ratio (MTR) and to compare the MTR values with normal values.Brain MTR in 28 PVL subjects (16 males, 12 females, gestational age 30.7+/-2.5 weeks ...
Maria Argyropoulou +2 more
exaly +4 more sources
Minocycline treatment following hypoxic/ischaemic injury attenuates white matter injury in a rodent model of periventricular leucomalacia [PDF]
Neuropathology and Applied Neurobiology, 2008 E Sabo, J J Volpe
exaly +2 more sources
Biallelic COL4A2 Variants Associated With Brain Small Vessel Disease and Brain Malformations. [PDF]
Clin GenetBiallelic COL4A2 variants cause a spectrum of brain abnormalities such as brain small vessel disease (BSVD). We describe two cases—one with cerebrovascular disruption and one with cortical malformations—expanding the recessive phenotype. Protein modeling reveals destabilization by p.(Arg179Cys), reinforcing its pathogenic role and highlighting collagen
Muhammad A +11 more
europepmc +2 more sources