Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Labor Certification for Permanent Immigrant Admissions [PDF]
[Summary] The foreign labor certification program in the U.S. Department of Labor (DOL) is responsible for ensuring that foreign workers do not displace or adversely affect working conditions of U.S. workers.
Wasem, Ruth Ellen
core +1 more source
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Dentition Type as a Determinant of Microbial Load Reduction by Antimicrobial Photodynamic Therapy in Deep Dentin Caries: A Systematic Review and Meta-analysis [PDF]
Statement of the Problem: Antimicrobial photodynamic therapy (aPDT) is a protocol proposed for reduction of bacterial load in deep dentin caries in primary and permanent dentitions.
Zahra Baghani +2 more
doaj +1 more source
Optimization of a 3D-Printed Permanent Magnet Coupling Using Genetic Algorithm and Taguchi Method [PDF]
Ekaterina Andriushchenko +6 more
openalex +1 more source
Louis I. Kahn fascinate us all with his passion for Mediterranean culture. Precisely at the moment when the center of the dominant culture moved from Europe to North America, he was able to immerse himself in the Roman brick structures of the great classical buildings, interpreting the timeless forms of antiquity.
openaire +3 more sources
Evaluation of Permanents [PDF]
The permanent of an m x n matrix A = (aij),m≤n, is defined bywhere the summation is over all one-to-one functions σ from {1, … ,m} to { 1, …,n}. In other words, the permanent of A is the sum of all thediagonal productsofA, that is, all the products ofmentries ofAno two of which lie in the same row or in the same column.
openaire +1 more source
Nutrition Status Correlated to the First Permanent Mandibular Molar Teeth of Elementary School Children in Lintau Buo, Tanah Datar Regency, West-sumatra [PDF]
The first permanent mandibular molar teeth is the most important for child, especially to stimulate growth of jaw. The teeth has normally erupted at children age of 6-7 years old. However, it is frequently not happened at this stage.
A, S. (Syukra)
core
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Simulation of the Braking Effects of Permanent Magnet Eddy Current Brake and Its Effects on Levitation Characteristics of HTS Maglev Vehicles [PDF]
Gaowei Zhang +9 more
openalex +1 more source

