Results 81 to 90 of about 3,528,368 (298)

Labor Certification for Permanent Immigrant Admissions [PDF]

open access: yes, 2003
[Summary] The foreign labor certification program in the U.S. Department of Labor (DOL) is responsible for ensuring that foreign workers do not displace or adversely affect working conditions of U.S. workers.
Wasem, Ruth Ellen
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Emancipated Youth Connections Project Final Report/Toolkit [PDF]

open access: yes, 2007
This report presents findings and recommendations from the Emancipated Youth Connections Project, a model program designed to seek and sustain permanent lifelong connections for older youth who have already emancipated from foster care without a ...
Cheryl J. Jacobson
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Anecic earthworms and associated ecosystem services in a ley-arable crop [PDF]

open access: yes, 2010
Een vruchtwisseling van gras en maïs zou duurzaam kunnen zijn in termen van nutriëntengebruik, maar het effect op regenwormen is nog onvoldoende bekend.
Bokhorst, J.G.   +5 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Agenesis of permanent canines: Rare case report

open access: yesDental Research Journal, 2017
Agenesis of permanent canines is a rare condition, and that of both maxillary and mandibular permanent canines is extremely rare. It may occur either isolated or in association with other dental anomalies.
Sumit Kumar Yadav   +3 more
doaj   +1 more source

Generalisation of Scott permanent identity

open access: yes, 2009
Scott considered the determinant of 1/(y-z)^2, with y,z running over two sets X,Y of size n, and determined its specialisation when Y and Z are the roots of y^n-a and z^n-b.
Lascoux, Alain
core   +2 more sources

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