Results 101 to 110 of about 3,528,368 (298)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

On order statistics from nonidentical discrete random variables

open access: yesOpen Physics, 2016
In this study, pf and df of single order statistic of nonidentical discrete random variables are obtained. These functions are also expressed in integral form.
Yüzbaşı Bahadır   +2 more
doaj   +1 more source

Unilateral fourth, fifth, sixth, and seventh molar in a nonsyndromic patient: A rare and unusual case report

open access: yesJournal of Indian Society of Pedodontics and Preventive Dentistry, 2017
Multiple supernumerary teeth are rare developmental anomalies which are often associated with syndromes. Only few examples of nonsyndromic supernumerary teeth have been reported with fourth, fifth, sixth, and seventh molar rarest of all.
Pallav Singhal   +3 more
doaj   +1 more source

Nutrition Status Correlated to the First Permanent Mandibular Molar Teeth of Elementary School Children in Lintau Buo, Tanah Datar Regency, West-sumatra [PDF]

open access: yes, 2012
The first permanent mandibular molar teeth is the most important for child, especially to stimulate growth of jaw. The teeth has normally erupted at children age of 6-7 years old. However, it is frequently not happened at this stage.
A, S. (Syukra)
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Approximating the Permanent of a Random Matrix with Vanishing Mean

open access: yes, 2018
We show an algorithm for computing the permanent of a random matrix with vanishing mean in quasi-polynomial time. Among special cases are the Gaussian, and biased-Bernoulli random matrices with mean 1/lnln(n)^{1/8}.
Eldar, Lior, Mehraban, Saeed
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Diplomatari de la Parròquia de Sant Cebrià de Valldoreix (1047-1447) [PDF]

open access: yes, 2012
El present estudi se centra en la transcripció de la documentació de la parròquia de Sant Cebrià de Valldoreix entre 1047 i ...
Seminari permanent de Paleografia,
core  

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