Results 61 to 70 of about 1,118,075 (318)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Transcendence and permanence

open access: yesDocomomo Journal, 2018
Louis I. Kahn fascinate us all with his passion for Mediterranean culture. Precisely at the moment when the center of the dominant culture moved from Europe to North America, he was able to immerse himself in the Roman brick structures of the great classical buildings, interpreting the timeless forms of antiquity.
openaire   +3 more sources

On the monotonicity of the permanent [PDF]

open access: yesProceedings of the American Mathematical Society, 1989
Let Ω n
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Comparative Evaluation of the Marginal Sealing Ability of two Commercially Available Pit and Fissure Sealants [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: The occlusal surfaces of the teeth usually have pits and fissures which provide a good environment for demineralization with minimal salivary access and make them caries prone.
Lakshmi Priya Sridhar   +3 more
doaj   +1 more source

PERMANENT CATHETERIZATION. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1901
n ...
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

La clef de la formation professionnelle offerte en milieu scolaire /

open access: yes, 1990
"Cet avis a été adopté par le Conseil permanent de la jeunesse à sa 14e séance, le 24 mars 1990"Bibliogr.: p. 41-43Notes bibliogr.
Québec (Province). Conseil permanent de la jeunesse   +1 more
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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