Results 111 to 120 of about 10,994,822 (334)

Observed and expected prevalence of permanent childhood hearing impairment in Oldham.

open access: yes, 2005
BACKGROUND: A perceived high prevalence of permanent childhood hearing impairment in Oldham, particularly in the Asian community, caused concern during the local implementation of the Newborn Hearing Screening Programme.
Mytton, Julie, Mackenzie, Ian
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

WP 18 - Permanent and transitory wage inequality of British men, 1975-2001: Year, age and cohort effects [PDF]

open access: yes
We examine the variance-covariance structure of log-wages over time and over the lifecycle of British men from 1975 to 2001, hereby controlling for cohort effects.
Alessie, R., Adriaan Kalwij
core  

Wage Effects of Non-wage Labour Costs [PDF]

open access: yes, 2014
We study wage effects of two important elements of non-wage labour costs: firing costs and payroll taxes. We exploit a reform that introduced substantial reduction in these two provisions for unemployed workers aged less than 30 and over 45 years who got
Cervini-Plá, María   +2 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Gender Differences and Social Capital Among Temporary and Permanent Migrants in China

open access: yes, 2016
Hukou, the Chinese household registration system, remains a significant barrier to Chinese internal migration. This paper uses panel data from the China Health and Nutrition Survey to look at individual, household, and community level predictors of ...
Hopping, Douglas
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Tax Policy and Consumer Spending: Evidence from Japanese Fiscal Experiments [PDF]

open access: yes
This paper studies the extent to which the impact of tax policy on consumer spending differs between temporary and permanent, as well as anticipated and unanticipated tax changes.
Takayuki Watanabe   +2 more
core  

THE MULTIETHNIC COEXISTENCE ON THE BALKANS [PDF]

open access: yesJournal of Process Management and New Technologies, 2014
The present perception of dialectic discourse of “conflict” and “permanent peace building” is creating a vision of two opposite, not just as dialectic but and by their content, and it presuppose that they cannot, or they should not exist together in
Strasko Stojanovski   +2 more
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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