Results 21 to 30 of about 26,150 (313)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Design of permanent magnet motor

IOP Conference Series: Materials Science and Engineering, 2020
Abstract The increasing energy demand is in line with population growth as well as the development of science and technology, and the maximum utilization of energy derived from magnets. The purpose of this research is to design of permanent magnet motor that produces rotation that can be utilized as power plant propulsion, without using ...
S H Susilo, Z Jannah, L D Mustofa, Y Effendhi   +3 more
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Exploring the Drive Motor of Electric Vehicles: Structure, Temperature Rises, and Operational Control of Permanent Magnet Motors

World Electric Vehicle Journal
The drive motor is a critical component of electric vehicles. The design of its structure, along with the regulation of temperature rises and operational control, significantly impact the overall performance of electric vehicles, affecting aspects such ...
Zhongxian Chen, Jiayin Liu
doaj   +1 more source

Development of sensorless vector control system for permanent magnet synchronous motor in Matlab Simulink

Записки Горного института, 2018
In last 20 years segment of electric drives with permanent magnet synchronous motors has increased. This type of motors has better technical characteristics compared to induction motors, but has problems in actual implementation, one of which is the ...
V. Ya. Frolov, R. I. Zhiliglotov
doaj   +1 more source

Overview of Position-Sensorless Technology for Permanent Magnet Synchronous Motor Systems

World Electric Vehicle Journal, 2023
In recent years, permanent magnet synchronous motors (PMSMs) have been widely used in industry. Position-sensorless control has the advantages of reducing costs and improving reliability, and is becoming one of the most promising technologies for ...
Yulei Xu, Ming Yao, Xiaodong Sun
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Electromagnetic-Thermal-Mechanical–Optimization Design of a 355 kW Three-Phase Variable Frequency PMSM

International Journal of Rotating Machinery
Focusing on the integrated multiphysics domain optimization design process for industrial permanent magnet motors, this paper presents the electromagnetic-thermal–rotor mechanical strength integrated design of a 355 kW, 1000 r/min industrial permanent ...
Shijun Chen, Xinyu Chen, Cheng Miao, Songchao Chu, Zeng Gu   +4 more
doaj   +1 more source

Analysis of the Saliency Ratio Effect on the Output Torque and the System Efficiency in IPM Drives

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2021
Permanent magnet synchronous motors (PMSM) can be classified into two groups based on the rotor saliency structure as surface mounted permanent magnet synchronous motors (SPM) and interior mounted permanent magnet synchronous motors (IPM). Saliency ratio
Mikail Koç, Osman Emre Özçiflikçi
doaj   +1 more source