Results 31 to 40 of about 125,107 (259)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Implantable Biosensors for Real-time Strain and Pressure Monitoring
Sensors, 2008 Implantable biosensors were developed for real-time monitoring of pressure and strain in the human body. The sensors, which are wireless and passive, consisted of a soft magnetic material and a permanent magnet.
Keat Ghee Ong +5 more
doaj +1 more source
A Two Strain Mutation Model with Temporary and Permanent Recovery
, 2022 Mutation occurs when there is a change in the sequence of the genetic code of an organism. Such changes pose some challenges especially in the development of drugs. A good understating of the dynamics of the strains will help to understand the variant of concern.
openaire +2 more sources
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Mechanical Engineering JournalEpoxy resin is widely used as a matrix resin of CFRP (Carbon Fiber Reinforced Plastics). It is known that the initial phase of the fatigue fracture of CFRP is the damage of matrix resin near fibers as well as interfacial debonding between fibers and ...
Yamato MORI +4 more
doaj +1 more source
Journal of the Mechanical Behavior of Materials, 2023 This research investigated the largest magnitude of displacement and horizontal tensile strain in several critical locations within the asphalt concrete (AC) layer in both the flexible pavement highway (FPH) and asphaltic overlayment track (AOT ...
Setiawan Dian M.
doaj +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Advances in Materials Science and Engineering, 2015 This paper presents the evaluation of permanent deformation of rubber-reinforced SMA asphalt mixtures by using dynamic creep test. The effect of trans-polyoctenamer as a cross-linking agent in permanent deformation of rubberized mixtures was also ...
Herda Yati Katman +4 more
doaj +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Seismic Response Sensitivity Analysis of Slope Anchorage Parameters in Open Pit Mine
Meikuang Anquan, 2020 By using FLAC3D software, the slope numerical model of anchorage open-pit mine is established, and the influence of anchorage parameters on dynamic response of bolt, displacement response of slope and plastic strain through length of slope is studied ...
LUO Ruixiang, YAN Zhixin, LIU Chunbo
doaj +1 more source