Results 41 to 50 of about 6,094,197 (290)

Assessment of Key Factors Impacting Permeability in Treated Firouzkooh Siliceous Sand and Hormuz Carbonate Sand Using Persian Gum Biopolymer [PDF]

پژوهش‌های زیرساخت‌های عمرانی
This study evaluates the performance of Persian gum as a new plant-based biopolymer in reducing the permeability of the Hormuz car-bonate sand and the Firouzkooh silicate sand.
Masoud Mohseninia, Hossein Salehzadeh
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Capillary‐Driven Backflow During Salt Precipitation in a Rough Fracture

Water Resources Research
Salt precipitation is a crucial process occurring during CO2 injection into saline aquifers. It significantly alters the porous space, leading to reduced permeability and impaired injectivity.
Xu‐Sheng Chen, Ran Hu, Chen‐Xing Zhou, Yang Xiao, Zhibing Yang, Yi‐Feng Chen   +5 more
doaj   +1 more source

Effects of a Dicalcium and Tetracalcium Phosphate-Based Desensitizer on In Vitro Dentin Permeability. [PDF]

PLoS ONE, 2016
The present study evaluated the effectiveness of a dicalcium and tetracalcium phosphate-based desensitizer in reducing dentin permeability in vitro. Dentin fluid flow was measured before and after treatment of dentin with patent dentinal tubules using 1 ...
Jianfeng Zhou, Ayaka Chiba, Debora L S Scheffel, Josimeri Hebling, Kelli Agee, Li-Na Niu, Franklin R Tay, David H Pashley   +7 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Clay Content Mediates the Contribution of Suspended Sporosarcina Pasteurii to Microbial Mineralization in Sandstones

Water Resources Research
Bioaugmented microbially induced carbonate precipitation (MICP) is a potentially useful tool for permeability modification of the subsurface. There is, however, uncertainty surrounding how the transport and mineralization capability of augmenting ...
E. M. Albalghiti, B. R. Ellis
doaj   +1 more source

Investigating tight oil reservoir production performance: Influence of geomechanical parameters and their distribution

Petroleum Research, 2023
Geomechanical properties have a prominent influence on reservoir stresses, which consequently reduce permeability and porosity with pressure depletion. These properties significantly affect the accuracy of reservoir modeling and recovery calculation, but
Sameera M. Hamd-Allah, Nagham Jasim Al-Ameri   +1 more
doaj   +1 more source