Results 161 to 170 of about 150,436 (290)

NheABC is a pH-dependent cytotoxin that targets mitochondria and contributes to the virulence of Bacillus cereus in wound infections. [PDF]

Cell Commun Signal
Ullah N, Yabrag A, Yska A, Pant R, Ramnath V, Lindbäck T, Carroll LM, Puthia M, Nadeem A.   +8 more
europepmc   +1 more source

Light‐Driven Quadrupedal Walking Biohybrid Robot With Antagonistic Muscle‐Rings and Inclined Joints

Advanced Robotics Research, EarlyView.
This work presents a light‐driven quadrupedal walking biohybrid robot powered by antagonistic muscle‐rings that achieve alternating walking gait. Optical training improved reproducibility of cultured muscle tissues, while caffeine treatment enhanced contractile force.
Shotaro Saito, Byeongwook Jo, Tomohiro Morita, Shota Noda, Minghao Nie, Shoji Takeuchi   +5 more
wiley   +1 more source

Permeabilized Cells

, 2019
openaire   +2 more sources

Permeabilized microbes in biotechnology [PDF]

Microbial Biotechnology, 2014
openaire   +2 more sources

Lipid tail length dictates membrane disruption by carmofur analogs and reveals noncanonical modes of action. [PDF]

RSC Adv
Chou C, Kasliwal A, Chen L, Hsu K, Anand A, Srivastava U, Vaidya S, Leung F, Yuyama E, Chepurna I, Gupta M, Quan L, Tsai N, Huang K, Kwok O, Zhang J, Tseng A, Gemma Do VT, Du E, Sarkar TJ, Yamamoto A, Laurienzo J, Pazzi J, Njoo E.   +23 more
europepmc   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Direct visualization of native GSDMD pores reveals lipid-driven stabilization during pyroptosis. [PDF]

Sci Adv
Kappelhoff S, Holtmannspötter M, Schaefer SL, Margheritis EG, Asik ÖD, Gehle N, Veit H, Danial JSH, Franzkoch R, Strauss S, Alvelid J, Koerfer A, Eggeling C, Psathaki OE, Jungmann R, Kurre R, Hummer G, Piehler J, Cosentino K.   +18 more
europepmc   +1 more source

A Pentaradial and Bilateral Combined Photoreception System in the Sea Cucumber is Mediated by a Blue Light‐Sensitive R‐Opsin

Advanced Science, EarlyView.
The sea cucumber Holothuria leucospilota detects blue and adjacent wavelengths of light via an r‐opsin with a maximum absorption at 459 nm. In the oral tentacles, papillae, and tube feet, distinct light‐sensing structures with specialized morphologies are formed, constituting a unique pentaradial and bilateral combined photoreception system.
Jiasheng Huang, Chunhua Ren, Zhou Qin, Yimeng Cui, Bingbing Zhang, Peng Luo, Xuan Wang, Yaoqi Xie, Xin Zhang, Aifen Yan, Yang Zhang, Dingding Fan, Yang Liu, Wenjie Pan, Xiao Jiang, Lihong Yuan, Haipeng Qin, David M. Irwin, Chaoqun Hu, Yang Liu, Ting Chen   +20 more
wiley   +1 more source

Acidic and alkaline conditions enhance Staphylococcus aureus α-toxin pore formation and cytotoxicity. [PDF]

PLoS Pathog
van der Linden TJ, Chatterjee A, Scheepmaker LM, Chakraborty D, Dutta S, Bardoel BW, Spaan AN.   +6 more
europepmc   +1 more source

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

Advanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen, Rong Chen, Wei Li, Bin Song, Ruiying Zhang, Lewei Dai, Yuwei Qi, Ruqian Chen, Yifan Xu, Hangbin Li, Jingyi Huang, Fangping Wu, Jianan Peng, Xinyu Wang, Yang Xiong, Chaofeng Mu, Guilin Cheng, Zhaoshen Li, Shanming Ruan, Lei Huang, Mancang Gu   +20 more
wiley   +1 more source