Use of the chemical permeabilization process in yeast cells: production of high-activity whole cell biocatalysts [PDF]
Yeast cells are popular microorganisms for use in various bioprocesses because of their ability to produce various enzymes. They are also known for their low price. However, the activity of these biocatalysts is limited by cell membrane diffusion. One of
ILONA TRAWCZYŃSKA
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Carbon monoxide prevents hepatic mitochondrial membrane permeabilization [PDF]
Background Low concentrations of carbon monoxide (CO) protect hepatocytes against apoptosis and confers cytoprotection in several models of liver. Mitochondria are key organelles in cell death control via their membrane permeabilization and the release ...
Alves Paula M +4 more
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Antimicrobial Activities and Mode of Flavonoid Actions
The emergence of antibiotics-resistant bacteria has been a serious concern for medical professionals over the last decade. Therefore, developing new and effective antimicrobials with modified or different modes of action is a continuing imperative.
Amal Thebti +8 more
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Introduction of Macromolecules into Bovine Adrenal Medullary Chromaffin Cells and Rat Pheochromocytoma Cells (PC12) by Permeabilization with Streptolysin O: Inhibitory Effect of Tetanus Toxin on Catecholamine Secretion [PDF]
Conditions are described for controlled plasma membrane permeabilization of rat pheochromocytoma cells (PC12) and cultured bovine adrenal chromaffin cells by Streptolysin O (SLO).
Ahnert-Hilger, G. +3 more
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Does the shape of the electric pulse matter in electroporation?
Electric pulses are widely used in biology, medicine, industry, and food processing. Numerous studies indicate that electroporation (EP) is a pulse-dependent process, and the electric pulse shape and duration strongly determine permeabilization efficacy.
Vitalij Novickij +3 more
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Previous studies suggest that the presence of antigen-specific polyfunctional T cells is correlated with improved pathogen clearance, disease control, and clinical outcomes; however, the molecular mechanisms responsible for the generation, function, and ...
Zachary R. Healy +2 more
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Membrane permeabilization by α-helical peptides: a flow cytometry study [PDF]
The permeabilization by α-helical peptides of nucleated mammalian cells can be monitored by flow cytometry. Ethidium bromide, a non fluorescent and poorly membrane permeant molecule, becomes strongly fluorescent only upon binding to DNA.
Midoux, Patrick +2 more
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Lysophosphatidylcholine-induced cellular injury in cultured fibroblasts involves oxidative events
Lysophosphatidylcholine (lysoPC), formed during LDL oxidation and located within atherosclerotic plaques, induces numerous cellular responses, but via unknown mechanisms.
Scott M. Colles, Guy M. Chisolm
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Temporary Membrane Permeabilization via the Pore-Forming Toxin Lysenin
Pore-forming toxins are alluring tools for delivering biologically-active, impermeable cargoes to intracellular environments by introducing large conductance pathways into cell membranes.
Nisha Shrestha +8 more
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A cardinal role for cathepsin D in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci [PDF]
The bactericidal function of macrophages against pneumococci is enhanced by their apoptotic demise, which is controlled by the anti-apoptotic protein Mcl-1.
Francis, S. E. +63 more
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