Results 91 to 100 of about 824,220 (237)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Elimination of Penicillin V by Membrane Process

open access: yesChemical Engineering Transactions, 2015
Recovery of penicillin V in wastewater from a membrane microfiltration process, aims to minimize the pharmaceutical pollution in our discharges. This study is carried out using a synthetic solution of penicillin V, at various concentrations, in a tubular
M. Samai, M. Chikhi, F. Zerara
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

What can functional transcranial Doppler ultrasonography reveal about the cerebral lateralization of writing

open access: yesFEBS Letters, EarlyView.
Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
wiley   +1 more source

Permeate flux modeling of membrane distillation

open access: yes, 1999
This paper concerns the modeling of membrane distillation. The model developed has been used to predict permeate fluxes using different initial operating conditions.
Vahdati, Maria
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

An approach to theoretical prediction of permeate flux decline in ultrafiltration

open access: yesDesalination and Water Treatment, 2009
Permeate flux decline was predicted by means of Song and Elimelech's [1] model. Theoretical results were compared with those obtained in ultrafiltration experiments where TMP and crossflow velocity were varied. Polyethylene glycol (PEG) of 35000 Da was used in the feed solution in a concentration of 10 g/L.
María-Cinta Vincent-Vela   +3 more
openaire   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Exponential model analysis of permeate flux for ultrafiltration in hollow-fiber modules by momentum balance

open access: yes, 2011
100學年度研究獎補助論文The modified correlation equation for predicting the permeate flux of membrane ultrafiltration (UF) in hollow-fiber modules was derived from the complete momentum balance coupled with the application of exponential model.
葉和明, Yeh, H.M.
core   +1 more source

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