Results 71 to 80 of about 708,611 (281)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Stable operation of MBR under high permeate flux
Water Practice and Technology, 2012 Permeate flux plays a critical role on the stable operation of membrane bioreactor (MBR) system for municipal wastewater treatment. The current commercially available submerged MBR systems, Zenon, Kobota, and Huber, etc. maintained their permeate fluxes at about 20–30 LMH to minimize the fouling potential of the membranes. A pilot scale MBR plant using
Y. Oda +5 more
openaire +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Changes in membrane specific permeate flux in both MBRs.
, 2013 Changes in membrane specific permeate flux in both MBRs.
Qiu Zhi-Gang (313442) +6 more
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Optimizing Direct Contact Membrane Distillation by RSM for Water Reclamation from Effluent of the RO Unit at Esfahan Refinery [PDF]
آب و فاضلاب, 2019 Considering the challenges faced and emphases being put in the last two decades on the water consumption at Esfahan Oil Refining Company (EORC), substantial efforts were made on its optimization and recovery of effluent from various unit operations.
Mohammad Ebadi +2 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
MembranesA new DCMD module design that introduces an insulation barrier of negligible thickness to divide the open duct of the hot-saline feed into two subchannels for dual-flow operation was investigated. This configuration enables one subchannel to operate in a
Chii-Dong Ho +3 more
doaj +1 more source