Results 101 to 110 of about 275,207 (346)

Evaluation and Prediction of Drug Permeation

open access: yesJournal of Pharmacy and Pharmacology, 1999
Abstract A major challenge confronting the pharmaceutical scientist is to optimize the selective and efficient delivery of new active entities and drug candidates. Successful drug development requires not only optimization of specific and potent pharmacodynamic activity, but also efficient delivery to the target site.
Pagliara, Alessandra   +4 more
openaire   +3 more sources

Wood Reconfiguration Enables Broadband Blackbody in Large‐Area, Modular, Optically Welded Carbon Constructs

open access: yesAdvanced Functional Materials, EarlyView.
Wood‐based broadband blackbody is achieved by reconfiguration of wood with lignin nanoparticles prior carbonization. Neglectable reflectivity from the visible to infrared wavelengths is obtained by combining thin nanostructures originated from the wood cell walls with long‐range microcavities in the wood lumina.
Bin Zhao   +7 more
wiley   +1 more source

Permeation characteristics of gramicidin conformers

open access: yesBiophysical Journal, 1988
To investigate the molecular origin of decreased conductance in variant gramicidin channels, we examined the current-voltage (IV) characteristics of single Val1-gramicidin A channels. Unlike standard channels, all variant channels showed pronounced rectification even though bathing solutions were symmetrical.
Gabor Szabo, David D. Busath
openaire   +3 more sources

Selective Benzene Capture by Metal‐Organic Frameworks

open access: yesAdvanced Functional Materials, EarlyView.
Metal‐organic frameworks (MOFs) hold significant potential for capturing benzene from air emissions and hydrocarbon mixtures in liquid phases. This capability stems from their precisely engineered structures, versatile chemistries, and diverse binding interactions.
Zongsu Han   +4 more
wiley   +1 more source

Effect of formulation factors on in vitro transcorneal permeation of voriconazole from aqueous drops

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2013
The purpose of this research was to evaluate the effect the formulation factors on in vitro permeation of voriconazole through freshly isolated goat and sheep corneas.
Biswaranjan Mohanty   +2 more
doaj   +1 more source

Quantitative Analysis of the Enhanced Permeation and Retention (EPR) Effect

open access: yesPLoS ONE, 2015
Tumor vasculature is characterized by a variety of abnormalities including irregular architecture, poor lymphatic drainage, and the upregulation of factors that increase the paracellular permeability.
Andrew D. Wong   +3 more
semanticscholar   +1 more source

Metal‐Organic Nanosheet Gels: Hierarchically Porous Materials for Selective Loading and Differential Release

open access: yesAdvanced Functional Materials, EarlyView.
A suspension of metal‐organic nanosheets was centrifuged to form self‐healing gels with a hierarchically porous structure. The prepared gels were used to selectively capture small molecules from solutions and differentially release them based on their size and charge. Abstract Metal‐organic nanosheets (MONs) are intrinsically porous 2D materials with a
Jiangtian Tan, Jonathan A. Foster
wiley   +1 more source

Observation of Hydrogen Permeation into Fresh Bearing Steel Surface by Thermal Desorption Spectroscopy

open access: yesTribology Online, 2011
This paper describes an experimental study on permeation of hydrogen into bearing steel through fresh surface with thermal desorption spectroscopy. Sliding experiments using a lapping machine with and without lubricant were conducted to generate fresh ...
Hiraku Tanimoto   +2 more
doaj   +1 more source

Highly Sensitive Electrochemical Biosensor Based on Hairy Particles with Controllable High Enzyme Loading and Activity

open access: yesAdvanced Functional Materials, EarlyView.
For the first time, a highly sensitive electrochemical biosensor based on SiO2‐based hairy particles with a grafted PDMAEMA polymer brush containing a quantifiable and large amount of immobilized Laccase is reported. The fabricated biosensor exhibits a sensitivity of 0.14 A·m⁻¹, a limit of detection (LOD) of 0.1 µm, and a detection range of 0.3–750 µm,
Pavel Milkin   +7 more
wiley   +1 more source

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