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Permeation enhancers in transdermal drug delivery: benefits and limitations
Expert Opinion on Drug Delivery, 2020Introduction: Transdermal drug delivery has several clinical benefits over conventional routes of drug administration. To open the transdermal route for a wider range of drugs, including macromolecules, numerous physical and chemical techniques to ...
Andrej Kováčik +2 more
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Ultrathin graphene-based membrane with precise molecular sieving and ultrafast solvent permeation.
Nature Materials, 2017Graphene oxide (GO) membranes continue to attract intense interest due to their unique molecular sieving properties combined with fast permeation. However, their use is limited to aqueous solutions because GO membranes appear impermeable to organic ...
Q. Yang +12 more
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Tissue dynamics with permeation
The European Physical Journal E, 2012Animal tissues are complex assemblies of cells, extracellular matrix (ECM), and permeating interstitial fluid. Whereas key aspects of the multicellular dynamics can be captured by a one-component continuum description, cell division and apoptosis imply material turnover between different components that can lead to additional mechanical conditions on ...
Jacques Prost +4 more
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Effects of Adhesives and Permeation Enhancers on the Skin Permeation of Captopril
Drug Development and Industrial Pharmacy, 2001To formulate a transdermal drug delivery system of captopril, monolithic adhesive matrix type patches containing 20% captopril, different pressure-sensitive adhesives, and various permeation enhancers were prepared using a labcoater. The effects of the adhesives and permeation enhancers on skin permeation of captopril from the prepared patches were ...
Yun-Seok Rhee +3 more
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Effect of Iontophoresis and Permeation Enhancers on the Permeation of an Acyclovir Gel
Current Drug Delivery, 2010The purpose of the present study was to explore the combined effect of chemical enhancers and iontophoresis on the in vitro permeation of acyclovir gel across porcine skin. Acyclovir gel was formulated using carbopol 940 and hydroxypropyl methylcellulose K4M (HPMC K4M). Effect of drug concentration on the delivery of acyclovir was examined.
Shailesh Koradia +6 more
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