Results 311 to 320 of about 272,073 (332)
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Intestinal Permeation Enhancers
Journal of Pharmaceutical Sciences, 2000This review addresses the field of improving oral bioavailability through the use of excipients that increase intestinal membrane permeability. The critical issues to consider in evaluating these approaches are 1) the extent of bioavailability enhancement achieved, 2) the influence of formulation and physiological variables, 3) toxicity associated with
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Calibration with permeation devices: is there a pressure dependence of the permeation rates?
Atmospheric Environment, 2004Permeation devices are often used for calibration purposes in atmospheric trace gas measurements. Compared to bottled gas standards, they have some advantages such as low cost, weight, and space requirements, and better long-term stability. For some devices, permeation rates have been reported to depend on pressure, and this dependence can lead to ...
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Estimating skin permeation. The validation of five mathematical skin permeation models
Chemosphere, 1995This study provides an analysis of the reliability of five mathematical models, simulating permeation of substances through the skin from aqueous solutions. An extensive database was generated, containing data on 123 measured permeation coefficients of 99 different chemicals and their physicochemical properties.
Wilschut, A. +3 more
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Polymer structure and gas permeation II. Permeation studies
Journal of Applied Polymer Science, 1963AbstractA series of gas permeability studies of plastic membranes demonstrated the strong dependence of gas transport on structural aspects of the membrane. Films of cellulose acetate butyrate, silicone rubber, polyethylene, polypropylene, and vinyl chloride, were used in these studies.
Karl Kammermeyer, R. W. Roberts
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Mucus permeating thiomer nanoparticles
European Journal of Pharmaceutics and Biopharmaceutics, 2015The aim of this study was to develop and evaluate a novel mucoadhesive drug delivery system based on thiolated poly(acrylic acid) nanoparticles exhibiting mucolytic properties to enhance particle diffusion into deeper mucus regions before adhesion. Mediated by a carbodiimide, cysteine and the mucolytic enzyme papain were covalently attached to poly ...
S. Köllner +5 more
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2014
Werfen wir einen R ckblick auf das urspr ngliche Ziel der Architektur trotz aller Debatten auf Thema -Form versus Funktion-, verstehen wir davon, dass es die simple Essenz eines Geb udes sein w rde, die Menschen bei den wesentlichen Bed rfnissen zu befriedigen, uns unsere t gliche Aktivit ten erf llen zu lassen.
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Werfen wir einen R ckblick auf das urspr ngliche Ziel der Architektur trotz aller Debatten auf Thema -Form versus Funktion-, verstehen wir davon, dass es die simple Essenz eines Geb udes sein w rde, die Menschen bei den wesentlichen Bed rfnissen zu befriedigen, uns unsere t gliche Aktivit ten erf llen zu lassen.
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The Impact of Permeation Enhancers on Transcellular Permeation of Small Molecule Drugs
The Journal of Physical Chemistry BPassive permeation through an epithelial membrane may be enhanced by using a class of amphiphilic molecules known as permeation enhancers (PEs). PEs have been studied in clinical trials and used in coformulations with peptides and small molecule drugs, and yet, an understanding of the permeant-PE interactions leaves much to be desired.
Mabel Bernaldez +4 more
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1970
For a discussion of the permeation of ions and of membrane potentials, the theoretical considerations concerning electrodiffusion of ions in homogeneous media (section 2.2.) are of utmost importance. However, the phenomena occurring on membranes—and especially on cell membranes—are more complicated than those in a homogeneous medium.
Karel Janáček, Arnošt Kotyk
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For a discussion of the permeation of ions and of membrane potentials, the theoretical considerations concerning electrodiffusion of ions in homogeneous media (section 2.2.) are of utmost importance. However, the phenomena occurring on membranes—and especially on cell membranes—are more complicated than those in a homogeneous medium.
Karel Janáček, Arnošt Kotyk
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1989
The wide range of polymer permeation properties were first observed and modelled over a century ago.1, 2 However, little further practical or theoretical work was undertaken until after the turn of the century when the need for improved pneumatic tyres developed.
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The wide range of polymer permeation properties were first observed and modelled over a century ago.1, 2 However, little further practical or theoretical work was undertaken until after the turn of the century when the need for improved pneumatic tyres developed.
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