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Effect of permeation enhancers and organic acids on the skin permeation of indapamide

International Journal of Pharmaceutics, 2008
The aim of present study was to investigate the transdermal properties of indapamide and to explore the efficacy of various permeation enhancers and organic acids with regard to the percutaneous absorption of indapamide. Permeation experiments were performed in vitro, using rat abdominal skin as a barrier. In the permeation studies, 2-chamber diffusion
Ligang Zhao   +5 more
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Permeation Number

2015
The permeation number expresses, for each species, a comparison (ratio) between two main transport mechanisms involved in a membrane separation unit.
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Intestinal Permeation Enhancers

Journal of Pharmaceutical Sciences, 2000
This review addresses the field of improving oral bioavailability through the use of excipients that increase intestinal membrane permeability. The critical issues to consider in evaluating these approaches are 1) the extent of bioavailability enhancement achieved, 2) the influence of formulation and physiological variables, 3) toxicity associated with
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The effect of permeation area ratio and shape on hydrogen permeation

Scripta Metallurgica et Materialia, 1994
It is generally agreed that the factors influencing permeation and diffusion hydrogen at room temperature are as follows: the thickness and surface condition of the specimen, composition, microstructure and grain size of the material, hydrogen traps and stress or strain conditions for the specimen, etc.
Wuyang Chu, Lijei Qiao, Lun Liu
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Effect of borneol on the transdermal permeation of drugs with differing lipophilicity and molecular organization of stratum corneum lipids

Drug Development and Industrial Pharmacy, 2016
The aim of the present paper was to investigate the promoting activity of borneol on the transdermal permeation of drugs with differing lipophilicity, and probe its alterations in molecular organization of stratum corneum (SC) lipids.
Q. Yi   +4 more
semanticscholar   +1 more source

Calibration with permeation devices: is there a pressure dependence of the permeation rates?

Atmospheric Environment, 2004
Permeation devices are often used for calibration purposes in atmospheric trace gas measurements. Compared to bottled gas standards, they have some advantages such as low cost, weight, and space requirements, and better long-term stability. For some devices, permeation rates have been reported to depend on pressure, and this dependence can lead to ...
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Polymer structure and gas permeation II. Permeation studies

Journal of Applied Polymer Science, 1963
AbstractA series of gas permeability studies of plastic membranes demonstrated the strong dependence of gas transport on structural aspects of the membrane. Films of cellulose acetate butyrate, silicone rubber, polyethylene, polypropylene, and vinyl chloride, were used in these studies.
Karl Kammermeyer, R. W. Roberts
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Estimating skin permeation. The validation of five mathematical skin permeation models

Chemosphere, 1995
This study provides an analysis of the reliability of five mathematical models, simulating permeation of substances through the skin from aqueous solutions. An extensive database was generated, containing data on 123 measured permeation coefficients of 99 different chemicals and their physicochemical properties.
Wilschut, A.   +3 more
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Mucus permeating thiomer nanoparticles

European Journal of Pharmaceutics and Biopharmaceutics, 2015
The aim of this study was to develop and evaluate a novel mucoadhesive drug delivery system based on thiolated poly(acrylic acid) nanoparticles exhibiting mucolytic properties to enhance particle diffusion into deeper mucus regions before adhesion. Mediated by a carbodiimide, cysteine and the mucolytic enzyme papain were covalently attached to poly ...
S. Köllner   +5 more
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Permeation

2014
Werfen wir einen R ckblick auf das urspr ngliche Ziel der Architektur trotz aller Debatten auf Thema -Form versus Funktion-, verstehen wir davon, dass es die simple Essenz eines Geb udes sein w rde, die Menschen bei den wesentlichen Bed rfnissen zu befriedigen, uns unsere t gliche Aktivit ten erf llen zu lassen.
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