Results 71 to 80 of about 282,952 (326)
Pharmaceutics, 2018 Background: The use of therapeutic antibodies for the treatment of neurological diseases is of increasing interest. Nose-to-brain drug delivery is one strategy to bypass the blood brain barrier.
Simone Ladel +9 more
doaj +1 more source
Proton block of proton-activated TRPV1 current. [PDF]
, 2015 The TRPV1 cation channel is a polymodal nociceptor that is activated by heat and ligands such as capsaicin and is highly sensitive to changes in extracellular pH. In the body core, where temperature is usually stable and capsaicin is normally absent, H(+)
Lee, Bo Hyun, Zheng, Jie
core +1 more source
Bayesian Estimation Improves Prediction of Outcomes After Epilepsy Surgery
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT We estimated the statistical power of studies predicting seizure freedom after epilepsy surgery. We extracted data from a Cochrane meta‐analysis. The median power across all studies was 14%. Studies with a median sample size or less (n ≤ 56) and a statistically significant result exaggerated the true effect size by a factor of 5.4, while the ...
Adam S. Dickey +4 more
wiley +1 more source
Jurnal Kimia Sains dan AplikasiPolyvinyl alcohol (PVA) modified chitosan-carboxymethyl chitosan (CMC) membrane has been successfully fabricated and used as a dialysis membrane. This research aims to examine the manufacturing process, characterization, and dialysis performance of CMC ...
Riska Nurfirda Annisa +3 more
doaj +1 more source
Multidimensional determination of pyr and dike [PDF]
Kom: Časopis za Religijske Nauke, 2017 In this paper the authors first analyse Aristotle's view of Heraclitus' philosophy, which is largely viewed through the prism of his quadruple causal scheme.
Kaluđerović Željko, Donev Dejan
doaj
Simulation studies of permeation through two-dimensional ideal polymer networks
, 2007 We study the diffusion process through an ideal polymer network, using numerical methods. Polymers are modeled by random walks on the bonds of a two-dimensional square lattice. Molecules occupy the lattice cells and may jump to the nearest-neighbor cells,
Antal T +11 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective Recent inflammatory bowel disease (IBD) treatment guidelines have recommended against nonsteroidal anti‐inflammatory drug (NSAID) use despite prevalent musculoskeletal symptoms and opioid overuse in this population. Given the discordance between changing national guidelines and potential clinical utility, we sought to assess national temporal
Adam S. Mayer +5 more
wiley +1 more source
Scientia Pharmaceutica, 2018 Superoxide dismutase (SOD) is an antioxidant protein. When administered orally, it has low bioavailability due to its low permeation. In a previous study we fused gliadin peptide P51 (LGQQQPFPPQQPYPQPQPF) and gliadin peptide P61 (QQPYPQPQPF) with SOD ...
Ratna Annisa Utami +3 more
doaj +1 more source
Financial Distress and Its Determinants in Rheumatoid Arthritis
Arthritis Care &Research, EarlyView.Objective To quantify the degree of financial distress and identify its determinants in adults with rheumatoid arthritis (RA) given the frequent prolonged use of expensive disease‐modifying therapies. Methods We identified adults enrolled in the FORWARD databank with either RA or noninflammatory musculoskeletal disease (NIMSKD) completing the ...
Amber Brown Keebler +5 more
wiley +1 more source
Preferential sorption versus preferential permeability in pervaporation [PDF]
, 1985 Transport of liquids by pervaporation takes place by a solution—diffusion mechanism. In order to investigate the “solution part” of this transport model, preferential sorption has been compared with preferential permeability.
Franken, T. +2 more
core +3 more sources