Results 121 to 130 of about 448,945 (257)
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Evaluation of the Scottish Borders Feuerstein Instrumental Enrichment (FIE) programme [PDF]
, 2006 In the light of decades of worldwide research that implies that the Feuerstein Instrumental Enrichment (FIE) programme has potential to enhance learning and attainment (Romney and Samuels, 2001) a pilot programme was launched in Scottish Borders Council ...
Scottish Executive (Funder) +4 more
core +1 more source
Applied SciencesUrban soils along transportation routes are subjected to intense anthropogenic pressure, altering their physicochemical properties and promoting the accumulation of potentially toxic metals (PTM).
Oimahmad Rahmonov +4 more
doaj +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Permissible campaign expenditures
, 1995 "November 20, 1995."; Discusses whether a candidate committee or an ongoing political committee (known as a PAC) can purchase computer equipment as a permissible expenditure under the state's campaign finance laws.; Harvested from the web on 9/5 ...
Janicki, Mary M.
core
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
INFLUENCE OF THE EMISSIONS OF COAL INDUSTRY ENTERPRISES ON PUBLIC HEALTH
Медицина в Кузбассе, 2017 Subject. The emissions of coal industry enterprises in Novokuznetsk. Objective. Assessment of ecological risk to the public health from the emissions of coal industry enterprises in Novokuznetsk. Methods.
Дмитрий Вячеславович Суржиков +2 more
doaj
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source