Results 71 to 80 of about 448,945 (257)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

The Content of Heavy Metals (Cu, Zn, Cr, Ni, Pb) in The Soil Near The Arterial Roads in Wroclaw (Poland)

E3S Web of Conferences, 2017
The concentrations of heavy metals in soils along the motorway bypass of Wroclaw (AOW) and the Eastern Ring Road of Wroclaw (WOW), Poland, have been determined.
Sobczyk Karolina, Hołtra Anna
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

The spatial distribution of potentially toxic elements in the mountain forest topsoils (the Silesian Beskids, southern Poland)

Scientific Reports
Progressive industrialisation and urbanisation in recent decades have dramatically affected the soil cover and led to significant changes in its properties, which inevitably affect the functioning of other components of the forest ecosystems.
Oimahmad Rahmonov, Michał Sobala, Dorota Środek, Dominik Karkosz, Sławomir Pytel, Małgorzata Rahmonov   +5 more
doaj   +1 more source

Permissible Floor Loading Diagram

, 2020
Permissible floor loading diagram.

core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Heavy Metal Contamination in Agricultural Soils of Central Bangladesh: Implications for Ecological Risk and Food Security [PDF]

Pollution
This study assessed the concentrations, distribution, sources and ecological risks of heavy metals in agricultural soils near industrial zones in Gazipur, Bangladesh.
Md. Humayun Kabir, Samir Ahmed Miazi, Rifat Shahid Shammi, Nowara Tamanna Meghla, Md. Sirajul Islam, Tanmoy Roy Tusher   +5 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Spatial learning in pigs: effects of environmental enrichment and individual characteristics on behaviour and performance [PDF]

, 2008
Contains fulltext : 77372.pdf (Publisher’s version ) (Closed access)This study investigated the effects of both environmental enrichment and individual behavioural characteristics on spatial cognitive capabilities of pigs, using a novel
Jarno Jansen, J. Elizabeth Bolhuis, Schouten, W.G.P., Spruijt, B.M., Willem G. P. Schouten, Wiegant, V.M., Bolhuis, J.E., Berry M. Spruijt, Jansen, J., Victor M. Wiegant, Jarno JarnoJansen   +10 more
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source