Results 121 to 130 of about 7,103,882 (305)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Critical evaluation of maximum permissible levels of microwave radiation
Arhiv za higijenu rada i toksikologiju, 1996 Prikazana su iskustva u vezi biološkog učinka mikrovalnog i elektromagnetskog zračenja niskih frekvencija. Posebno se razmatra pitanje tzv. ekstratermalnog efekta. Na temelju prethodno provedenih ispitivanja autor zastupa u prikazu mišljenje da treba uzeti u obzir i taj učinak ove vrste zračenja.
openaire +2 more sources
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Evaluative Uncertainty and Permissible Preference [PDF]
There has recently been an explosion of interest in rational and moral choice under evaluative uncertainty—uncertainty about values or reasons. However, the dominant views on such choice have at least three major problems: they are overly demanding, they
Horton, Joe, Ross, Jacob
core +1 more source
[Substantiation of the maximum permissible level of ambush in the air].
Gigiena i sanitariia, 1991 The article is devoted to the substantiation of ambush MAC in the ambient air. Resorptive action of the insecticide on the organism of experimental animals has been studied under the conditions of 3-month 24-hour chronic inhalational exposure. On the basis of the studies the maximum single and average 24-hour ambush MACs in the ambient air have been ...
R A, Kasymov, Sh M, Mirzaev
openaire +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Permissible campaign expenditures
, 1995 "November 20, 1995."; Discusses whether a candidate committee or an ongoing political committee (known as a PAC) can purchase computer equipment as a permissible expenditure under the state's campaign finance laws.; Harvested from the web on 9/5 ...
Janicki, Mary M.
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