Results 31 to 40 of about 594,037 (266)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Koncese v českém správním právu

open access: yesActa Universitatis Carolinae Iuridica, 2020
The article examines standardized administrative acts called concessions. It seeks to describe concessions as the theory of administrative law understands them, find their characteristics and distinguish them from other administrative acts.
Gabriela Göttelová
doaj   +1 more source

An Access Control Method based on Scenario Trust [PDF]

open access: yesInternational Journal of Computational Intelligence Systems, 2012
Access control is an important element in network security. Meanwhile, trust provides a new direction for access control in open network environments. Based on the dynamic nature of trust, we study the temporal and spatial characteristics in the security
Shunan Ma, Jingsha He, Xunbo Shuai
doaj   +1 more source

A Critique of Shiite Jurists and Civil Law’s Popular Opinion Concerning Unauthorized Marriage [PDF]

open access: yesفقه و حقوق خانواده, 2017
In this article the meaning of an ‘unauthorized marriage’ has been evaluated from the point of view of Shiite Scholars and civil law. The different opinions presented have been stated and the bases of each one have been separately examined.
seyed mohamad mahdi saber   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Android Malware Detection Based on API Pairing

open access: yesXibei Gongye Daxue Xuebao, 2020
Aiming at the problem that the permission-based detection is too coarse-grained, a malware detection method based on sensitive application program interface(API) pairing is proposed.

doaj   +1 more source

The Nature and the Enforcement of Father’s Permission on Children's Marriage [PDF]

open access: yesفقه و حقوق خانواده, 2014
Since the ratification of Article 1041 of the civil code in 1313 (1934 AD) the legal age of marriage and the status of child marriage in Iranian law, has had it ups and downs. Closing the gap between the legal age of marriage to that of natural (physical)
Mohammad Abedi
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Effect of Guardian's Permission on Girl's Marriage [PDF]

open access: yesفقه و حقوق خانواده, 2009
Guardian's permission on girl's marriage is one of the controversial issues in society. The presents article studies the various theological and legal views regarding guardian's permission on girl's marriage and the extend of rights Islam has given to ...
Fa'ezeh Azimzadeh Ardebili
doaj   +1 more source

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