Results 51 to 60 of about 592,420 (266)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Task-role-based Access Control Model in Smart Health-care System

MATEC Web of Conferences, 2015
As the development of computer science and smart health-care technology, there is a trend for patients to enjoy medical care at home. Taking enormous users in the Smart Health-care System into consideration, access control is an important issue ...
Wang Peng, Jiang Lingyun
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Preparation of Ethic codes for studies on laboratory animals

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2006
In most of research programs, uses of laboratory animals are necessary. For this reason we have to prepare comfortable and health situation near their natural life for animals in laboratory.
SJ Ale davoud, A Javazadeh blouri, H Sadeghi,, MAM Sabzghabaie, SM Latifi, R Nourouzian, B Larijani   +6 more
doaj  

Formalizing Permission to Delegate and Delegation with Policy Interaction

Sensors
In the context of Internet of Things (IoT) intelligent systems, the latest research regarding delegation using an access control model has gained attention, reflecting the need for models to support more functionalities in relation to hierarchical ...
Azan Hamad Alkhorem, Daniel Conte de Leon, Ananth A. Jillepalli, Jia Song   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

DEVELOPMENT OF LEGISLATION ON HUMAN CLONING: WORLD EXPERIENCE AND A PROMISING LEGAL MODEL FOR MODERN RUSSIA

RUDN Journal of Law, 2020
The relevance of the research is due to the invariance of approaches to the legal regulation of public relations in the field of human cloning, the need for semantic differentiation of the concept of cloning, which ensures formation of an adequate ...
Fyodor V. Fetyukov
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Qualification of the Organization and Carrying Out Gambling in the Gambling Zone Based on the Permission Got Illegally

Èkonomika, Pedagogika i Pravo, 2016
In this article author takes up questions of qualification of the organization and carrying out gamblings in a gambling zone based on the permission got illegally which are treated as illegal business activity.
Boris R. Avetisyan
doaj