Results 71 to 80 of about 3,133,021 (299)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Using 'dead or dependent' as an outcome measure in clinical trials in Parkinson's disease [PDF]
, 2014 Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.Peer reviewedPublisher ...
Counsell, Carl +4 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
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The most economical power factor correction according to tariff structures in Egypt [PDF]
, 2005 This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services. Internal or personal use of this material is permitted.
Aziz, MMA, Zobaa, AF
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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Preparation of Ethic codes for studies on laboratory animals
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2006 In most of research programs, uses of laboratory animals are necessary. For this reason we have to prepare comfortable and health situation near their natural life for animals in laboratory.
SJ Ale davoud +6 more
doaj
Formalizing Permission to Delegate and Delegation with Policy Interaction
SensorsIn the context of Internet of Things (IoT) intelligent systems, the latest research regarding delegation using an access control model has gained attention, reflecting the need for models to support more functionalities in relation to hierarchical ...
Azan Hamad Alkhorem +3 more
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RUDN Journal of Law, 2020 The relevance of the research is due to the invariance of approaches to the legal regulation of public relations in the field of human cloning, the need for semantic differentiation of the concept of cloning, which ensures formation of an adequate ...
Fyodor V. Fetyukov
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The optimal passive filters to minimize voltage harmonic distortion at a load bus [PDF]
, 2005 This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services. Internal or personal use of this material is permitted.
Zobaa, AF
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