Results 81 to 90 of about 3,133,021 (299)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Qualification of the Organization and Carrying Out Gambling in the Gambling Zone Based on the Permission Got Illegally

open access: yesÈkonomika, Pedagogika i Pravo, 2016
In this article author takes up questions of qualification of the organization and carrying out gamblings in a gambling zone based on the permission got illegally which are treated as illegal business activity.
Boris R. Avetisyan
doaj  

Poetic permission -A Historical and Artistic Study

open access: yesمجلة كلية الفقه, 2007
The Present study is concerned with one of the oldest literary phenomenon, i.e – Al –Ejaza Al– Shi'riya which flourished in Pre – Islamic poetry and continued in late periods , A brief note is first tiren about the concept and terminology of this ...
Dr. Muzahim Matar Hussein
doaj   +1 more source

Capacitive compensation at nonsinsoidal buses based on IEEE Std. 18-1992 [PDF]

open access: yes, 2003
This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services. Internal or personal use of this material is permitted.
Zobaa, AF
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Lego – Building a European Concept of Functionality [PDF]

open access: yes, 2010
Reproduced with permission of the ...
Liakatou, V, Maniatis, S
core  

Antidepressants in pregnancy and breastfeeding [PDF]

open access: yes, 2007
Copyright © 2007 Australian Prescriber Reproduced with permission from Australian Prescriber The document attached has been archived with permission from the publisher/copyright holder.Maternal depression and anxiety during pregnancy and the early years ...
Sved-Williams, A.
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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