Results 111 to 120 of about 192,401 (288)
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Permissive belief revision (preliminary report
, 1999 We point out that current belief revision opera-tions can be used to revise non-monotonic the-ories and we propose a new operation, called permissive belief revision.
Cachopo, João P. +7 more
core +2 more sources
Everyday norms have become more permissive over time and vary across cultures
Communications PsychologyEvery social situation that people encounter in their daily lives comes with a set of unwritten rules about what behavior is considered appropriate or inappropriate.
Kimmo Eriksson +163 more
doaj +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Norme permissive et droit public
, 2006 The notion of permissive norm is presented as contradictory: how could a legal rule not impose anything to its addressee ? Its presence in the public law is all the more vague as the discipline is considered printed by unilatelarism and marked by the ...
Groulier, Cédric
core +2 more sources
FEBS Open Bio, EarlyView.Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court +3 more
wiley +1 more source
Hubungan Antara Pola Asuh Permissive Indulgent Dan Interaksi Sosial Dengan Kematangan Emosi
Analitika, 2016 Penelitian ini bertujuan untuk mengetahui hubungan pola asuh permissive indulgent dan interaksi sosial dengan kematangan emosi pada siswa SMA Negeri 2 Medan. Sampel dalam penelitian ini adalah siswa SMA Negeri 2 Medan berjumlah 88 orang.
Meutia Fajar Sari Nasution
doaj