Results 61 to 70 of about 393,562 (266)

Experimental-use Permits

open access: yesEDIS, 2005
Experimental use of pesticides refers to formal research efforts conducted to scientifically assess the pest control potential of a registered pesticide or an experimental pesticide. This document is PI-56, one of a series of the Agronomy Department, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of ...
openaire   +3 more sources

International Instrument on Permitted Uses in Copyright Law [PDF]

open access: yesIIC - International Review of Intellectual Property and Competition Law, 2021
Hilty, Reto M.   +14 more
openaire   +5 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Investigation of Halal Status and Permitted Industrial Utilization of Carmine Dye in Iran [PDF]

open access: yesJournal of Food Quality and Hazards Control
Background: The limited arable land for producing animal and plant-based foods has compelled governments to explore foods and additives from uncommon sources such as insects.
M. Moslemi   +4 more
doaj  

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Piercing and tattoos in adolescents: legal and medico-legal implications

open access: yesOpen Medicine, 2018
Non-therapeutic body modification interventions are permitted within the limits of the use of one’s own body that can be specified in the legal system.
Conti Adelaide   +7 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

INJECTABLE HYALURONIC ACID DRUGS FOR THE TREATMENT OF KNEE OSTEOARTHRITIS IN THE CONTEXT OF EVIDENCE-BASED MEDICINE

open access: yesНаучно-практическая ревматология, 2018
To evaluate the efficacy and safety of intraarticular hyaluronic acid (HA) in osteoarthritis (OA), the authors have analyzed the scientific publications included in foreign databases (Medline/PubMed) on the relevant laboratory, experimental, and clinical
A. I. Petukhov   +2 more
doaj   +1 more source

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