Results 101 to 110 of about 329,666 (328)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
A product for permutation groups and topological groups [PDF]
Duke Mathematical Journal, 2017 Updated to match version published in Duke Math. J.
openaire +4 more sources
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
On induced permutation matrices and the symmetric group [PDF]
, 1936 A. C. Aitken
openalex +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
QUASI-PERMUTATION REPRESENTATIONS OF METACYCLIC 2-GROUPS [PDF]
Journal of Sciences, Islamic Republic of Iran, 1998 By a quasi-permutation matrix we mean a square matrix over the complex field C with non-negative integral trace. Thus, every permutation matrix over C is a quasipermutation matrix.
doaj
Representation of a group as a transitive permutation group [PDF]
, 1931 G. A. Miller
openalex +1 more source
Imprimitive permutations in primitive groups
Journal of Algebra, 2017 The goal of this paper is to study primitive groups that are contained in the union of maximal (in the symmetric group) imprimitive groups. The study of types of permutations that appear inside primitive groups goes back to the origins of the theory of permutation groups. However, this is another instance of a situation common in mathematics in which a
Peter J. Cameron +6 more
openaire +6 more sources
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source