Results 91 to 100 of about 116,618 (260)

An Accept-and-Reject Algorithm to Sample from a Set of Permutations Restricted by a Time Constraint

open access: yesJournal of Statistical Software, 2006
A modification of an accept-and-reject algorithm to sample from a set of restricted permutations is proposed. By concentrating on a special class of matrices obtained by restriction of the permutation in time, assuming the objects to be permuted to be ...
Johannes Hüsing
doaj  

Review about the Permutation Approach in Hypothesis Testing

open access: yesMathematics
Today, permutation tests represent a powerful and increasingly widespread tool of statistical inference for hypothesis-testing problems. To the best of our knowledge, a review of the application of permutation tests for complex data in practical data ...
Stefano Bonnini   +2 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Coin’s Package Permutation Tests Graphic User Interface Extension for R Commander [PDF]

open access: yesApplied Medical Informatics, 2011
Background: For small, skewed, sparse, unbalanced data, or data with lots of ties the exact P values computed with permutation tests can help making valid statistical inferences.
Daniel-Corneliu LEUCUŢA
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Combined Permutation Tests for Pairwise Comparison of Scale Parameters Using Deviances

open access: yesStats
Nonparametric combinations of permutation tests for pairwise comparison of scale parameters, based on deviances, are examined. Permutation tests for comparing two or more groups based on the ratio of deviances have been investigated, and a procedure ...
Scott J. Richter, Melinda H. McCann
doaj   +1 more source

Assessing keyness using permutation tests

open access: yes, 2023
We propose a resampling-based approach for assessing keyness in corpus linguistics based on suggestions by Gries (2006, 2022). Traditional approaches based on hypothesis tests (e.g. Likelihood Ratio) model the copora as independent identically distributed samples of tokens.
openaire   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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