Results 161 to 170 of about 476,988 (354)
AbstractLet n,k be positive integers, with k⩽n, and let τ be a fixed permutation of {1,…,k}.11We will often refer to {1,2,…,k} as the letters on which the permutation acts, however their numerical sizes will be very relevant. We will call τ the pattern. We will look for the pattern τ in permutations σ of n letters.
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Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Generalized pattern avoidance with additional restrictions
Babson and Steingr\'{\i}msson introduced generalized permutation patterns that allow the requirement that two adjacent letters in a pattern must be adjacent in the permutation.
Kitaev, Sergey
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A Recurrence for Permutations without Rising or Falling Successions [PDF]
John Riordan
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Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
Permutations of sequences and the Schröder-Bernstein theorem [PDF]
Paul R. Halmos
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This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
A Remark on the Group Rings of Order Preserving Permutation Groups [PDF]
Robert LaGrange, A. H. Rhemtulla
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AbstractWith any permutation g of a set Ω is associated a partition of Ω into the cycles of g. What information do we get about a group G of permutations if we know either the set or the multiset of partitions of Ω, or of partitions of n=|Ω|, which arise as the cycle partitions of its elements? Some partial answers to these questions are given.
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