Results 61 to 70 of about 141,402 (295)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
On disjoint cross intersecting families of permutations [PDF]
Discrete Mathematics Letters, 2022 Nuttanon Songsuwan +4 more
doaj +1 more source
On the sub-permutations of pattern avoiding permutations
Discrete Mathematics, 2014 There is a deep connection between permutations and trees. Certain sub-structures of permutations, called sub-permutations, bijectively map to sub-trees of binary increasing trees. This opens a powerful tool set to study enumerative and probabilistic properties of sub-permutations and to investigate the relationships between 'local' and 'global ...
DISANTO, FILIPPO, Wiehe T.
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A new generation tree for permutations, preserving the number of fixed points [PDF]
Discrete Mathematics & Theoretical Computer Science, 2014 We describe a new uniform generation tree for permutations with the specific property that, for most permutations, all of their descendants in the generation tree have the same number of fixed points.
Philippe Duchon, Romaric Duvignau
doaj +1 more source
On permutations and permutation polytopes [PDF]
, 1978 An easy characterization is given of neighbors on permutation polytopes. Using this characterization it is shown that the graph of any such polytope is Hamiltonian, and that the diameter is two.
openaire +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
On Minimal Strings Containing the Elements of S_n by Decimation [PDF]
Discrete Mathematics & Theoretical Computer Science, 2001 The permutations by decimation problem is thought to be applicable to computer graphics, and raises interesting theoretical questions in combinatory theory.We present the results of some theoretical and practical investigation into this problem.We show ...
Robert Erra, Nik Lygeros, Nigel Stewart
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Inflations of geometric grid classes of permutations [PDF]
, 2015 All three authors were partially supported by EPSRC via the grant EP/J006440/1.Geometric grid classes and the substitution decomposition have both been shown to be fundamental in the understanding of the structure of permutation classes.
Ruskuc, Nik, Albert, M.D., Vatter, V.
core +1 more source