Results 81 to 90 of about 108,510 (269)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

ADAPTIVE REORDERING OF OBSERVATION SPACE TO IMPROVE PATTERN RECOGNITION

open access: yesTASK Quarterly, 2007
The problem of observation space reordering is presented as a novel approach to pattern recognition based on non-parametric, combinatorial statistical tests. It consists in linearly ordering the elements of a discrete multi-dimensional observation space
JULIUSZ L. KULIKOWSKI
doaj  

Log-Convexity and Fixed Points of Permutations

open access: yesAxioms
We provide a combinatorial proof for the fact that the numbers of derangements of length n form a log-convex sequence for n≥3. A minor modification of our proof yields the same result for permutations of length n≥4 that have exactly one fixed point.
Miklós Bóna
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

SYNTHESIS OF REVERSE TWO-BIT DUAL-OPERATED STRICTLY STRAIGHT CRYPTOGRAPHIC CODING ON THE BASIS OF ANOTHER OPERATION

open access: yesСучасні інформаційні системи, 2019
Based on the analysis of a group of two-bit two-operand operations of strict stable cryptographic coding, the relations between direct and inverse operations are established and formalized and their correctness is proved.
Volodymir Rudnitsky   +4 more
doaj   +1 more source

Crossings and Permutations [PDF]

open access: yes, 2006
We investigate crossing minimization problems for a set of permutations, where a crossing expresses a disarrangement between elements. The goal is a common permutation π* which minimizes the number of crossings. This is known as the Kemeny optimal aggregation problem minimizing the Kendall-τ distance.
Therese Biedl   +2 more
openaire   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Permutation statistics of products of random permutations

open access: yesAdvances in Applied Mathematics, 2014
Given a permutation statistic $s : S_n \to \mathbb{R}$, define the mean statistic $\bar{s}$ as the statistic which computes the mean of $s$ over conjugacy classes. We describe a way to calculate the expected value of $s$ on a product of $t$ independently chosen elements from the uniform distribution on a union of conjugacy classes $Γ\subseteq S_n$.
openaire   +3 more sources

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