Results 91 to 100 of about 108,510 (269)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The shallow permutations are the unlinked permutations
, 2022 Diaconis and Graham studied a measure of distance from the identity in the symmetric group called total displacement and showed that it is bounded below by the sum of length and reflection length. They asked for a characterization of the permutations where this bound is an equality; we call these the shallow permutations.
openaire +2 more sources
Permutations of a Multiset Avoiding Permutations of Length 3
European Journal of Combinatorics, 2001 A sequence of numbers \(\alpha =(a_{1},\dots ,a_{m})\) is contained in a sequence of numbers \(\beta =(b_{1},\dots ,b_{n})\) if there is a subsequence \((b_{i_{1}},\dots,b_{i_{m}})\), \(i_{1}
Michael H. Albert +4 more
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Discrete Mathematics, 2011 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Michael H. Albert +4 more
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Generation of cycle permutation graphs and permutation snarks
Mathematics of ComputationWe present an algorithm for the efficient generation of all pairwise non-isomorphic cycle permutation graphs, i.e. cubic graphs with a $2$-factor consisting of two chordless cycles, non-hamiltonian cycle permutation graphs and permutation snarks, i.e. cycle permutation graphs that do not admit a $3$-edge-colouring.
Jan Goedgebeur +2 more
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Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Counting permutations where the difference between entries located r places apart can never be s (for any given positive integers r and s) [PDF]
Enumerative Combinatorics and Applications, 2023 George Spahn, Doron Zeilberger
doaj +1 more source