Results 101 to 110 of about 108,510 (269)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Counting parking sequences and parking assortments through permutations [PDF]
Enumerative Combinatorics and Applications, 2023 Spencer J. Franks +4 more
doaj +1 more source
Minimizing the Height of Simple Tangles
Journal of Graph Algorithms and ApplicationsA tangle $T$ of height $h$ describes the ordering of $n$ elements called wires on each of $h$ levels. A pair of wires $ab$ is called a swap. Between any two adjacent levels only the ordering of adjacent wires may swap and each wire may participate in ...
Jakob Baumann, Ignaz Rutter
doaj +1 more source
Permutation and local permutation polynomials of maximum degree
Afrika MatematikaAbstract Let $$\mathbb {F}_q$$ F q be the finite field with q elements and $$\mathbb {F}_q[x_1,\ldots , x_n]$$
Gutierrez Gutierrez, Jaime +1 more
openaire +5 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Logical limit laws for layered permutations and related structures
Enumerative Combinatorics and Applications, 2021 Samuel Braunfeld, Matthew Kukla
doaj +1 more source
Discrete Mathematics, 1988 The concept of separation of an ordered pair of permutations is introduced and a discrete analogue of Jordan curve theorem, based on this separation, is proved. As the author mentions, his result provides an elementary though somewhat involved proof of the original topological version of this theorem.
openaire +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source