Results 201 to 210 of about 1,277,726 (395)

Double Cross‐Linked Hydrogel for Intra‐articular Injection as Modality for Macrophages Metabolic Reprogramming and Therapy of Rheumatoid Arthritis

open access: yesAdvanced Functional Materials, EarlyView.
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song   +8 more
wiley   +1 more source

Engineering a Single Amino Acid Bionanozyme for Ultrasensitive Detection of Biomarkers: A WHO‐REASSURE‐ Aligned Approach

open access: yesAdvanced Functional Materials, EarlyView.
A unique 2D bionanozyme, engineered from a single amino acid and copper ions, demonstrates peroxidase‐mimicking catalytic activity. This efficient and simple bionanozyme allows for ultrasensitive, equipment‐free visual detection of key biomarkers in both test and real samples, meeting the WHO‐REASSURE standards for practical diagnostic applications ...
Subrat Vishwakarma   +5 more
wiley   +1 more source

Evolving Platinum‐Copper Nanostructures for Enhanced Photothermal Therapy and Controlled Copper Release in Cancer Therapy

open access: yesAdvanced Functional Materials, EarlyView.
Platinum‐Copper bimetallic nanoparticles may evolve depending on their synthesis under tumor microenvironment conditions and play a dual role as chemotherapeutic agents after releasing Cu ions and as near infrared photothermal agents with the Pt‐rich remaining frames.
Jose I. Garcia‐Peiro   +7 more
wiley   +1 more source

Magnetically Guided Mechanoactive Mineralization Scaffolds for Enhanced Bone Regeneration

open access: yesAdvanced Functional Materials, EarlyView.
A 3D‐printed ‘rebar‐concrete’ inspired scaffold (PGS‐P@MGel) synergizes spontaneous biomineralization with magneto‐mechanical stimulation through PDA@Fe3O4‐embedded hydrogel. This dual biointerface activates Piezo1/β‐catenin/YAP mechanotransduction axis, enhancing BMSCs osteogenesis and angiogenesis simultaneously.
Xuran Guo   +10 more
wiley   +1 more source

Rotating Liquid Marble Microreactors for Enhanced Enzymatic Reactions

open access: yesAdvanced Functional Materials, EarlyView.
Dynamic magnetic liquid marbles (LMs), stabilized by hydrophobic magnetic proteinaceous colloidosomes, function as effective microreactors for enzymatic processes. Precise magnetic manipulation allows for the rotation of these LMs, enhancing the efficiency of the enzymatic cascade reaction both at the air/water interface and within biphasic enzyme ...
Weijie Jiang   +5 more
wiley   +1 more source

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