Results 241 to 250 of about 736,089 (295)

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

Advanced Science, EarlyView.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang, Qingwen Huang, Zhuo Chen, Weijian Meng, Hongliang Dong, Zhihong Qi, Liang Liu, Jie Shen, Daxing Xie   +8 more
wiley   +1 more source

Omics Analysis of Lignin Degradation by the Gut Microbiomes of Wood-Eating Hypomeces squamosus Fabricius. [PDF]

Microbiologyopen
Mao C, Zhang Q, Zhang J, Li X.
europepmc   +1 more source

CD207‐Positive Dendritic Cells Promote Emphysema Through CD8+ T Cell Pathway in Chronic Obstructive Pulmonary Disease

Advanced Science, EarlyView.
CD207+ dendritic cells (DCs) drive emphysema by promoting CD8⁺ T cell cytotoxicity via Birbeck granule‐dependent MHC‐I antigen presentation. This DC subset is expanded by cigarette smoke‐induced oxidative stress, which triggers granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) release from airway epithelium.
Shurui Xuan, Yunhui Wu, Feng Liu, Heng Fu, Yaqi Meng, Yingwei Ou, Xijing Yuan, Ian M. Adcock, Man Jia, Xiaoning Zeng, Xin Yao   +10 more
wiley   +1 more source

The Effect of Conjugated Bilirubin on the Measurement of Unbound Bilirubin. [PDF]

Acta Paediatr
Kleinfeld A, Huber A, Oh W, Hegyi T.
europepmc   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

Advanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu, Jing Luo, Li Yu, Daoxi Qi, Boyu Li, Yating Chen, Chen Wang, Xiaokang Zhang, Wenzheng Guo, Qiyong Lou, Gang Zhai, Yonglin Ruan, Jianfei Huang, Shengchi Shi, Zhan Yin, Fang Zheng   +15 more
wiley   +1 more source

Kinetic, Spectral, and Structural Characterization of a Heme-Containing Peroxidase From the Skin of <i>Cucurbita maxima</i>. [PDF]

Biochem Res Int
Jackson A, Thompson I, Cochrane E, Ware A, Byrum R, Buxa L, Farmer C, Medina H, Raner GM.   +8 more
europepmc   +1 more source

Effect of activated charcoal and subculture rates on a two-phase culture strategy involving biomass accumulation followed by phenolic production in date palm cell suspension cultures. [PDF]

BMC Plant Biol
Abohatem MA.
europepmc   +1 more source

Highly Active and Stable Au@Pt Nanozymes-Based Colorimetric Nucleic Acids Detection for Varicella-Zoster Virus Diagnosis. [PDF]

Int J Nanomedicine
Zong M, Liu F, Long L, Liu J, Wu X.
europepmc   +1 more source

Validation and performance assessment of a commercial anti-peroxidasin antibody. [PDF]

Histochem Cell Biol
Brandão I, Silva R, Gomes B, Almeida JR, Oliveira JP, Alencastre IS.   +5 more
europepmc   +1 more source