Results 241 to 250 of about 1,115,092 (313)

NUP85 Mediates Endoplasmic Reticulum Stress through the USP47/ASK1 Signaling Pathway to Regulate the Progression of Liver Fibrosis

Advanced Science, EarlyView.
In the present study, we have demonstrated that the NUP85‐USP47‐ASK1 signaling pathway may have regulated the progression of liver fibrosis through modulating ERS. Additionally, we have developed a CREKA‐coupled liposome to target delivery of MV, a pharmacological inhibitor of NUP85, to activated HSCs, thereby attenuating liver fibrosis. ABSTRACT Liver
Dashuai Yang, Haoran Yang, Linxin Pan, Chang Tian, Fucheng Zuo, Shilei Huang, Xianrui Li, Ming Chen, Cheng Qian, Jie Wang, Zhaolin Chen, Tao Xu   +11 more
wiley   +1 more source

Comparative analysis of enzymatic defence mechanisms in Sapindus mukorossi Gaertn. and Acacia concinna (Willd.) DC. using a Michaelis-Menten kinetic model. [PDF]

Sci Rep
Parmar R, Varsani V, Dudhagara D, Gamit S, Naghera N, Kothari R, Vyas S.   +6 more
europepmc   +1 more source

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source

Thyroid peroxidase gene variants and susceptibility to congenital hypothyroidism and autoimmune thyroid disease among Egyptian pediatric cohort. [PDF]

Clin Exp Pediatr
Sakhr HM, Hassan MH, Abdallah EA, Ewis AM, Mohamed MH, Rizk SG.   +5 more
europepmc   +1 more source

Interphase cytogenetics in paraffin embedded sections from human testicular germ cell tumor xenografts and in corresponding cultured cells [PDF]

, 1989
Cremer, Thomas, Emmerich, Patricia, Hofmann, M. C., Jauch, Anna, Walt, H.   +4 more
core  

Adaptive responses of pear cultivars to low-temperature stress in the spring period. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Mishko AE, Klyukina AV.
europepmc   +1 more source

Generation and modulation of catalytically relevant states of a dye-decolourizing peroxidase using time-resolved serial femtosecond crystallography with drop-on-chip mixing and X-ray-driven reduction. [PDF]

Acta Crystallogr D Struct Biol
Lučić M, Glerup J, Aller P, Axford D, Devenish N, Park J, Shilova A, Landeros de la Isla A, Strange RW, Zhou T, Owen RL, Worrall JAR, Hough MA.   +12 more
europepmc   +1 more source

Preliminary Investigation on Salivary Enzymes of Massese Sheep. [PDF]

Animals (Basel)
Sagona S, Di Rosso A, Coppola F, Boni CB, Russo C, Palego L, Betti L, Giannaccini G, Felicioli A, Casini L.   +9 more
europepmc   +1 more source

Spatiotemporal Dynamics of the Eco-Physiological Characteristics of <i>Picea schrenkiana</i> in the Tianshan Mountains and Its Adaptive Mechanisms. [PDF]

Plants (Basel)
Li R, Gong L, Wu X, Yin K, Niu Y, Sun X, Abay P, Tian F.   +7 more
europepmc   +1 more source

Horseradish peroxidase assisted "signal-on" chemiluminescence aptasensor for sensitive detection of aflatoxin B1. [PDF]

RSC Adv
Sun L, Miao F, Wan W, Wang L, Dong C.
europepmc   +1 more source